---
title: A Medication Adherence Intervention for HIV Infected Veterans
nct_id: NCT00013065
overall_status: COMPLETED
sponsor: US Department of Veterans Affairs
study_type: OBSERVATIONAL
primary_condition: HIV Infection
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT00013065.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT00013065"
ct_last_update_post_date: 2015-04-07
last_seen_at: "2026-05-12T07:18:03.613Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# A Medication Adherence Intervention for HIV Infected Veterans

**NCT ID:** [NCT00013065](https://clinicaltrials.gov/study/NCT00013065)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 210
- **Lead Sponsor:** US Department of Veterans Affairs
- **Conditions:** HIV Infection
- **Completion Date:** 2003-12
- **CT.gov Last Update:** 2015-04-07

## Brief Summary

It is estimated that the VHA is caring for nearly 40 percent of all HIV-infected veterans. To benefit from recent improvements in anti-HIV therapy, patients need to take their medications consistently.

## Detailed Description

Background:

It is estimated that the VHA is caring for nearly 40 percent of all HIV-infected veterans. To benefit from recent improvements in anti-HIV therapy, patients need to take their medications consistently.

Objectives:

Optimizing health for HIV patients requires excellent adherence to antiretroviral medication regimens. However, its unclear how best to incorporate adherence education and support programs into VA HIV outpatient care. We implemented and evaluated a pharmacist program (ACE) and a Pager reminder program to support adherence in veterans with HIV.

Methods:

We used a quasi-experimental design with pre-post evaluation at four VA Centers. Three treatment conditions (ACE, Pager, Usual Care) were rolled-in sequentially over two study phases, allowing for group comparisons between conditions. ACE is a multi-component manualized 4-session, individual patient education and support program by trained pharmacists. The Pager intervention used alphanumeric pagers to remind patients of dosing times. Electronically-monitored medication adherence (MEMS), self-report questionnaires, and pharmacy refill records were collected. Qualitative site interviews were collected before and after interventions to assist with program evaluation. Multilevel mixed models were used to analyze main study outcomes over time. Secondary analyses compared subgroup who actually received all ACE sessions (�as treated�) to controls.

Status:

Project has been completed and Final Report submitted to HSR\&D CO.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 65 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

Patients must be greater than or equal to 18 years old, must be enrolled in HIV Primary care at one of 4 VA study sites and be taking antiretroviral therapy.

Exclusion Criteria:
```

## Arms

- **Group 1**

## Locations (4)

- Southern Arizona VA Health Care System, Tucson, AZ, Tucson, Arizona, United States
- VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California, United States
- VA San Diego Healthcare System, San Diego, CA, San Diego, California, United States
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles, California, United States

## Recent Field Changes (last 30 days)

- `sponsor.lead` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `locations.southern arizona va health care system, tucson, az|tucson|arizona|united states` — added _(2026-05-12)_
- `locations.va palo alto health care system, palo alto, ca|palo alto|california|united states` — added _(2026-05-12)_
- `locations.va san diego healthcare system, san diego, ca|san diego|california|united states` — added _(2026-05-12)_
- `locations.va greater los angeles healthcare system, west los angeles, ca|west los angeles|california|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT00013065.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT00013065*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*