---
title: Spread of Dermatophytes Among Families
nct_id: NCT00233493
overall_status: COMPLETED
sponsor: University Hospitals Cleveland Medical Center
study_type: OBSERVATIONAL
primary_condition: Onychomycosis
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT00233493.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT00233493"
ct_last_update_post_date: 2024-11-01
last_seen_at: "2026-05-12T07:26:25.285Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Spread of Dermatophytes Among Families

**Official Title:** Demonstration of the Spread of Dermatophytes Through Casual Contact Among Family Household Members

**NCT ID:** [NCT00233493](https://clinicaltrials.gov/study/NCT00233493)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 50
- **Lead Sponsor:** University Hospitals Cleveland Medical Center
- **Collaborators:** Novartis Pharmaceuticals
- **Conditions:** Onychomycosis, Tinea Pedis
- **Start Date:** 2005-03
- **Completion Date:** 2013-05
- **CT.gov Last Update:** 2024-11-01

## Brief Summary

The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.

## Detailed Description

Enrolled families consist of at least two members over the age of 14. Once the index person is examined and a dermatophyte is isolated from either toenail or foot scale, other family members are examined and cultured. All dermatophyte isolates obtained from each family unit are compared using DNA typing and restriction length polymorphism (RFLP) to determine whether family members share the same organism or were infected by an outside source.

## Eligibility

- **Minimum age:** 14 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria: positive dermatophyte culture

\-

Exclusion Criteria:

* use of antifungal agents, either oral or topical
```

## Primary Outcomes

- **Dermatophyte Species Distribution** _(time frame: Baseline)_ — To identify dermatophytes isolates known to cause onychomycosis and/or tinea pedis by Polymerase Chain Reaction (PCR)

## Secondary Outcomes

- **Dermatophyte Strain Types Among All Enrolled Households** _(time frame: Baseline)_
- **Number of Households With Dermatophyte Infection Spread** _(time frame: Baseline)_
- **Number of Participants Affected by the Association of Spread of Infection and History of Tinea Pedis or Onychomycosis** _(time frame: Baseline)_

## Locations (1)

- University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.university hospitals cleveland medical center|cleveland|ohio|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT00233493.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT00233493*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*