---
title: Differential Metabolic Effects of Statins
nct_id: NCT00546559
overall_status: COMPLETED
sponsor: Gachon University Gil Medical Center
study_type: OBSERVATIONAL
primary_condition: Hypercholesterolemia
countries: South Korea
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT00546559.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT00546559"
ct_last_update_post_date: 2008-08-29
last_seen_at: "2026-05-12T06:58:24.785Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Differential Metabolic Effects of Statins

**NCT ID:** [NCT00546559](https://clinicaltrials.gov/study/NCT00546559)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Lead Sponsor:** Gachon University Gil Medical Center
- **Conditions:** Hypercholesterolemia
- **Start Date:** 2004-01
- **Completion Date:** 2008-03
- **CT.gov Last Update:** 2008-08-29

## Brief Summary

The investigators hypothesized simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients.

## Eligibility

- **Minimum age:** 25 Years
- **Maximum age:** 75 Years
- **Sex:** ALL

```
Inclusion Criteria:

* Low-density lipoprotein cholesterol levels \> 130

Exclusion Criteria:

* Overt liver disease,
* Chronic renal failure
* Hypothyroidism
* Myopathy
* Uncontrolled diabetes
* Severe hypertension
```

## Interventions

- **statins (simvastatin, pravastatin)** (DRUG)

## Primary Outcomes

- **Simvastatin and pravastatin may have differential metabolic effects in hypercholesterolemic patients.**

## Locations (1)

- Gil Medical Center, Incheon, South Korea

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.gil medical center|incheon||south korea` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT00546559.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT00546559*  
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