---
title: Effectiveness of a Family-Based Intervention for Adolescent Suicide Attempters (The SAFETY Study)
nct_id: NCT00692302
overall_status: COMPLETED
phase: PHASE1, PHASE2
sponsor: University of California, Los Angeles
study_type: INTERVENTIONAL
primary_condition: Suicide
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT00692302.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT00692302"
ct_last_update_post_date: 2025-03-30
last_seen_at: "2026-05-12T07:11:10.585Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Effectiveness of a Family-Based Intervention for Adolescent Suicide Attempters (The SAFETY Study)

**Official Title:** Family Based Intervention for Adolescent Suicide Attempters

**NCT ID:** [NCT00692302](https://clinicaltrials.gov/study/NCT00692302)

## Key Facts

- **Status:** COMPLETED
- **Phase:** PHASE1, PHASE2
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 72
- **Lead Sponsor:** University of California, Los Angeles
- **Collaborators:** National Institute of Mental Health (NIMH)
- **Conditions:** Suicide
- **Start Date:** 2006-03
- **Completion Date:** 2019-10-18
- **CT.gov Last Update:** 2025-03-30

## Brief Summary

This study will evaluate the effectiveness of an individually tailored suicide prevention treatment program called SAFETY in reducing suicide and suicide attempts in adolescents.

## Detailed Description

Suicide is consistently a leading cause of death among adolescents in the United States, making suicide prevention a serious public health concern. The risk factors for suicide vary but are often related to depression and other mental disorders, substance abuse, a major stressful event, and family history of suicide. Despite the morbidity and mortality associated with suicide attempts in adolescents, there is a lack of empirically supported treatment strategies and consensus regarding the best practices for suicide prevention. The SAFETY intervention is an individually tailored treatment strategy that integrates family- and community-based interventions and cognitive behavioral therapy and links youth to needed services and resources. SAFETY may be an effective means of reducing suicide attempts and improving mental health in at-risk adolescents. This study will evaluate the effectiveness of SAFETY in reducing suicide and suicide attempts in adolescents.

This study will be divided into two phases. Participants in Phase I will all receive 12 weeks of the family-based cognitive behavioral therapy intervention SAFETY. Phase I will be used to develop the intervention manual, protocols, and adherence measures for SAFETY in Phase II. Phase I participants will undergo assessments at baseline and Week 12. Assessments will last 90 minutes and will include a series of interviews and questionnaires concerning family, general health, and mental health-related issues.

Participants in Phase II will be assigned randomly to receive 12 weeks of SAFETY or enhanced usual care. The frequency of sessions, which will involve both youth and parent participants, will vary on the basis of the individual needs of participants. SAFETY sessions will be individually tailored for each participant's specific needs and will include the following elements: (1) family- and community-based interventions aimed at mobilizing family and community networks that support youth safety, adaptive behavior, and reasons for living; (2) cognitive behavioral treatment modules that focus on decreasing suicidality and preventing repeat suicide attempts; and (3) an individualized care linkage strategy that links youth to needed services and resources. At baseline, Week 12, and Month 6, all youth and parent participants will undergo the same assessments that were performed during Phase I.

## Eligibility

- **Minimum age:** 12 Years
- **Maximum age:** 19 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Suicide attempt or repetitive self-harm in the 3 months before study entry

Exclusion Criteria:

* Psychosis
* Substance dependency
* Immediate risk of out-of-home placement
* Symptoms/conditions that would interfere with assessment and/or intervention protocols
```

## Arms

- **SAFETY I** (EXPERIMENTAL) — Phase I participants who will receive SAFETY
- **SAFETY II** (EXPERIMENTAL) — Phase II participants who will receive SAFETY
- **Control** (ACTIVE_COMPARATOR) — Phase II participants who will receive enhanced usual care

## Interventions

- **SAFETY** (BEHAVIORAL) — Participants will receive a family-based cognitive behavioral therapy intervention called SAFETY for 12 weeks. The SAFETY intervention is an individually tailored intervention strategy that integrates (1) family- and community-based interventions aimed at mobilizing family and community networks that support youth safety, adaptive behavior, and reasons for living; (2) cognitive behavioral treatment modules that focus on decreasing suicidality and preventing repeat suicide attempts; and (3) an individualized care linkage strategy that links youth to needed services and resources.
- **Enhanced usual care** (BEHAVIORAL) — Enhanced usual care will include treatment as usual enhanced by study support.

## Primary Outcomes

- **Suicide Attempt** _(time frame: 3-months)_ — Derived from adapted C-SSRS that incorporates questions from the Suicide History Interview
- **Suicide-related hospitalizations** _(time frame: Measured at month 3)_ — SACA, adapted

## Locations (1)

- University of California, Los Angeles, California, United States

## Recent Field Changes (last 30 days)

- `armsInterventions.arms` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.university of california|los angeles|california|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT00692302.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT00692302*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*