---
title: Studies on the H Pipelle, a New Device for Endometrial Sampling at Hysteroscopy
nct_id: NCT00755651
overall_status: COMPLETED
phase: NA
sponsor: Royal Free Hampstead NHS Trust
study_type: INTERVENTIONAL
primary_condition: Abnormal Uterine Bleeding
countries: United Kingdom
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT00755651.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT00755651"
ct_last_update_post_date: 2008-09-19
last_seen_at: "2026-05-12T07:09:14.785Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Studies on the H Pipelle, a New Device for Endometrial Sampling at Hysteroscopy

**NCT ID:** [NCT00755651](https://clinicaltrials.gov/study/NCT00755651)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 180
- **Lead Sponsor:** Royal Free Hampstead NHS Trust
- **Conditions:** Abnormal Uterine Bleeding
- **Start Date:** 2003-01
- **Completion Date:** 2007-05
- **CT.gov Last Update:** 2008-09-19

## Brief Summary

The investigators have developed a novel instrument for taking endometrial biopsies at no touch (vaginoscopic) hysterectomy which avoids the need to instrument the vagina with speculums and tenaculums, and also avoids the possible need for cervical dilatation. The investigators wish to study the ease of use and efficacy of the new device compared with traditional techniques of endometrial sampling at hysteroscopy.

## Detailed Description

We have developed a novel instrument for taking endometrial biopsies at no touch (vaginoscopic) hysterectomy which avoids the need to instrument the vagina with speculums and tenaculums, and also avoids the possible need for cervical dilatation. We wish to study the ease of use and efficacy of the new device compared with traditional techniques of endometrial sampling at hysteroscopy in terms of biopsy adequacy, the time taken to obtain a biopsy and patient experience.

## Eligibility

- **Minimum age:** 20 Years
- **Maximum age:** 80 Years
- **Sex:** FEMALE
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Indication to carry out diagnostic hysteroscopy
* Agrees and is suitable for outpatient/office hysteroscopy

Exclusion Criteria:

* Failed outpatient/office hysteroscopy
```

## Arms

- **H Pipelle** (EXPERIMENTAL) — Endometrial sample obtained using the H Pipelle
- **Pipelle** (ACTIVE_COMPARATOR) — Endometrial sample obtained with standard Pipelle

## Interventions

- **Endometrial biopsy** (PROCEDURE) — Endometrial biopsy taken on completion of office/outpatient diagnostic hysteroscopy

## Primary Outcomes

- **Discomfort** _(time frame: End of procedure)_

## Secondary Outcomes

- **Procedure time, biopsy adequacy** _(time frame: End of procedure)_

## Locations (1)

- Royal Free Hospital, London, United Kingdom

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.royal free hospital|london||united kingdom` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT00755651.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT00755651*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*