---
title: Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma Patients
nct_id: NCT00902109
overall_status: UNKNOWN
sponsor: University Hospital Tuebingen
study_type: OBSERVATIONAL
primary_condition: Primary Open Angle Glaucoma (POAG)
countries: Germany
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT00902109.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT00902109"
ct_last_update_post_date: 2016-02-02
last_seen_at: "2026-05-12T07:24:12.285Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma Patients

**Official Title:** Pilot Study to Compare the Humphrey Field Analyzer (HFA) 30-2 Swedish Interactive Threshold Algorithm (SITA) Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE), Using a New Fast GATE (German Adaptive Threshold Estimation) in Glaucoma Patients Under Topic Therapy

**NCT ID:** [NCT00902109](https://clinicaltrials.gov/study/NCT00902109)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 12
- **Lead Sponsor:** University Hospital Tuebingen
- **Collaborators:** Alcon Research
- **Conditions:** Primary Open Angle Glaucoma (POAG)
- **Start Date:** 2010-04
- **Completion Date:** 2016-12
- **CT.gov Last Update:** 2016-02-02

## Brief Summary

The purpose of this study is to compare the two psychophysical perimetric techniques regarding progression of the visual field.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* primary open angle glaucoma (POAG)
* spherical ametropia max. ± 8 dpt
* cylindrical ametropia max. ± 3 dpt
* distant visual acuity \> 10/20
* pupil diameter \> 3 mm

Exclusion Criteria:

* diabetic retinopathy
* asthma
* history of epilepsy or significant psychiatric disease
* medications known to effect visual field sensitivity
* infections (e.g., keratitis, conjunctivitis, uveitis)
* severe dry eyes
* miotic drug
* squint
* nystagmus
* albinism
* any ocular pathology, in either eye, that may interfere with the ability to obtain visual fields
* keratoconus
* intraocular surgery (except for uncomplicated cataract surgery) performed \< 3 month prior to screening
* history or signs of any visual pathway affection other than glaucoma
* history or presence of macular disease and/or macular edema, ocular trauma, medications known to affect visual field sensitivity
```

## Arms

- **perimetry, HRT, OCT** — perimetry, HRT, OCT

## Interventions

- **Perimetry** (DEVICE) — different perimetric devices, different perimetric grids: Octopus: New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) HFA: 30-2, Sita (Swedish Interactive Thresholding Algorithm) full threshold
- **Confocal Scanning Laser Tomography** (DEVICE) — HRT examinations for the clinical evaluation of the optic disc.
- **Optical Coherence Tomography (OCT)** (DEVICE) — imaging of the retinal nerve fiber layer

## Primary Outcomes

- **Comparison of rate of progression** _(time frame: 36 month)_ — Perimetric measures every 3 month over 3 years

## Locations (1)

- Institute for Ophthalmic Research, Tübingen, Germany

## Recent Field Changes (last 30 days)

- `outcomes.primary` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.institute for ophthalmic research|tübingen||germany` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT00902109.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT00902109*  
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