---
title: The Sinonasal Outcome Test - 22, Validated for Danish Patients
nct_id: NCT01254916
overall_status: COMPLETED
sponsor: Odense University Hospital
study_type: OBSERVATIONAL
primary_condition: Chronic Rhinosinusitis
countries: Denmark
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01254916.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01254916"
ct_last_update_post_date: 2012-05-08
last_seen_at: "2026-05-12T07:27:24.313Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# The Sinonasal Outcome Test - 22, Validated for Danish Patients

**NCT ID:** [NCT01254916](https://clinicaltrials.gov/study/NCT01254916)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 44
- **Lead Sponsor:** Odense University Hospital
- **Conditions:** Chronic Rhinosinusitis
- **Start Date:** 2008-10
- **Completion Date:** 2009-03
- **CT.gov Last Update:** 2012-05-08

## Brief Summary

Introduction: Chronic rhinosinusitis (CRS) is a significant health problem increasing in both incidence and prevalence. It calls into attention consensus about diagnosing, assessing symptoms and treatment of patients with CRS. Therefore a validated Danish measure of health-related quality of life in sinonasal disease is needed.

Method: The Sinonasal Outcome measure 22 (SNOT-22) was translated into Danish and reproducibility was evaluated by test-retesting 40 patients with CRS. The statistical analyses used, were Pearson´s correlation coefficient, Cronbach´s alfa, Kappa and Bland-Altman´s Plot. Reproducibility was also tested looking at subscales within the SNOT-22.

Result: The results show good internal correlation with Cronbach´s alfa at 0.83 in the initial test and 0.92 in the retest. Pearson was 0.70 (p\<0.001) revealing good correlation between the initial scores and the retests scores. Kappa was calculated for each item with a mean value of 0.61 showing substantial agreement. Paired t-test revealed no significant difference in the subscales.

Conclusion: The Danish version of SNOT-22 is recommended for Danish clinicians and researches as a patient-reported measure of outcome in sino-nasal disorders such as rhinosinusitis and nasal polyposis.

## Eligibility

- **Minimum age:** 15 Years
- **Maximum age:** 75 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria: Persons diagnosed with Chronic Rhinosinusitis -

Exclusion Criteria: Change of treatment or acute change of symptoms due to common cold/influenza in the time between completing the test and the retest. If SNOT-score was very low. Persons who left before offered test or declined testing.

\-
```

## Arms

- **Patients with chronic rhinosinusitis**

## Primary Outcomes

- **Reproducibility of Sinonasal Outcome test 22** _(time frame: From the time of fullfilling the first SNOT-22 to fullfilling the second SNOT-22 after 14 days)_

## Locations (1)

- Department of Otorhinolaryngology, Odense University Hopsital, Odense, Denmark

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.department of otorhinolaryngology, odense university hopsital|odense||denmark` — added _(2026-05-12)_

---

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