---
title: Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort
nct_id: NCT01303432
overall_status: COMPLETED
phase: NA
sponsor: Bioiberica
study_type: INTERVENTIONAL
primary_condition: Low Intensity Knee Gonalgia
countries: Spain
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01303432.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01303432"
ct_last_update_post_date: 2012-09-14
last_seen_at: "2026-05-12T07:24:49.013Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort

**Official Title:** Double-blind, Placebo-controlled Nutrition Intervention Trial, to Study Efficacy and Safety of Yogurts Supplemented With Mobilee on Joint Function, Joint Structure and Quality of Life of Adults With Low Intensity Gonalgia

**NCT ID:** [NCT01303432](https://clinicaltrials.gov/study/NCT01303432)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 80
- **Lead Sponsor:** Bioiberica
- **Collaborators:** Technological Centre of Nutrition and Health
- **Conditions:** Low Intensity Knee Gonalgia
- **Start Date:** 2010-09
- **Completion Date:** 2011-06
- **CT.gov Last Update:** 2012-09-14

## Brief Summary

The purpose of this study is to determine whether the daily eating of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia.

## Detailed Description

The prevalence of low intensity gonalgia is relatively high in western population. The purpose of the present intervention study is to determine whether the daily consumption of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia. Previous research using in vitro and animal models have demonstrated the efficacy of Mobilee in reducing inflammation and promoting anabolic responses in joint tissues. In addition, in two previous human intervention trials, the effects of Mobilee in joint function had been assessed using isokinetic tests. The present trial aims to confirm those previous results.

## Eligibility

- **Minimum age:** 20 Years
- **Maximum age:** 70 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Adult (between 20 and 70 years of age)
* Subject with low intensity knee gonalgia (VAS pain intensity between 3 and 5cm during at least the last 6 months)
* Healthy individual according to its medical records, physical and laboratorial parameters
* Positive informed consent

Exclusion Criteria:

* Individuals requiring acetaminophen or any other drug to control pain
* Active rheumatoid arthritis or any other inflammatory joint disease
* Oral treatment with corticosteroids 4 weeks before selection
* Intra-articular treatment with corticosteroids 3 months before selection
* Significant injury of the study joint 12 months before selection
* Individuals receiving any drug or supplement for osteoarthritis
* Individuals requiring any type of medical prescription to control pain
```

## Arms

- **Mobilee yogurt** (EXPERIMENTAL) — Subjects eating daily on yogurt supplemented with Mobilee
- **Placebo yogurt** (PLACEBO_COMPARATOR) — Subjects receiving daily a standard yogurt

## Interventions

- **Yogurt supplemented with Mobilee** (DIETARY_SUPPLEMENT) — One yogurt (125mL) per day including 80mg of Mobilee
- **Yogurt** (DIETARY_SUPPLEMENT) — One yogurt (125mL) per day

## Primary Outcomes

- **Change from baseline in isokineic assessment of muscular strength** _(time frame: 3 months)_ — The muscular isokinetic assessment determines peak torque, power mean and total work of a certain joint using a dynamometric computerized system. The principal parameter is the change from baseline in the peak torque of the affected joint in extension at a speed of 240º/sec measured in Nm (Newton-meter).

## Secondary Outcomes

- **Change from baseline in isokinetic assessment of muscular strength (other conditions)** _(time frame: 3 months)_
- **Assessment of joint swelling, effusion** _(time frame: 3 months)_
- **Pain assessment (VAS)** _(time frame: 3 months)_
- **SF-36 Health questionnaire** _(time frame: 3 months)_
- **Number of Participants with Adverse Events** _(time frame: 3 months)_
- **Subjective evaluation of the intervention** _(time frame: 3 months)_
- **Change from baseline in systolic blood pressure, hearth rate, general biochemical profile and body mass index at 3 months** _(time frame: 3 months)_

## Locations (1)

- Hospital Universitari Sant Joan de Reus, Reus, Tarragona, Spain

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.hospital universitari sant joan de reus|reus|tarragona|spain` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT01303432.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT01303432*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*