---
title: High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Total Endoprosthesis
nct_id: NCT01335815
overall_status: UNKNOWN
sponsor: Heidelberg University
study_type: OBSERVATIONAL
primary_condition: Perioperative Myocardial Infarctions
countries: Germany
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01335815.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01335815"
ct_last_update_post_date: 2011-04-14
last_seen_at: "2026-05-12T06:47:06.813Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Total Endoprosthesis

**Official Title:** High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Knee and Hip Endoprosthesis

**NCT ID:** [NCT01335815](https://clinicaltrials.gov/study/NCT01335815)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 200
- **Lead Sponsor:** Heidelberg University
- **Conditions:** Perioperative Myocardial Infarctions, Pulmonary Embolism
- **Start Date:** 2011-03
- **Completion Date:** 2013-03
- **CT.gov Last Update:** 2011-04-14

## Brief Summary

Summary: The purpose of the study is to prove if the biomarker high sensitive troponin T (hsTnT) and the biomarker of endogenous stress copeptin can serve as surrogate parameter of prognosis in patients with elective knee and hip total endoprosthesis.

## Detailed Description

Consecutively, high sensitive troponin T and copeptin will be measured in all patients with elective knee and hip endoprosthesis in the orthopedic department of the University of Heidelberg. The blood is taken during the routine blood testes if possible, on admission and the days 1-4 following the operation. Usual baseline characteristics are taken as well as usual blood results (hb, cholesterol and so on). Primary endpoint is the detection of perioperative myocardial infarction and pulmonary embolism.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Consecutive patients with elective knee and hip endoprosthesis

Exclusion Criteria:

* Not willing or not able to take part in the observational trial
* No written inform consent
```

## Arms

- **elective knee and limb endoprothesis**

## Primary Outcomes

- **Prevalence of perioperative myocardial infarction and pulmonary embolism** _(time frame: Until 96h after operation)_

## Locations (1)

- University of Heidelberg, Heidelberg, Baden-Wurttemberg, Germany — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.university of heidelberg|heidelberg|baden-wurttemberg|germany` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT01335815.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT01335815*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*