---
title: Risk Factors for Residual Neoplasia After Endoscopic Mucosal Resection
nct_id: NCT01478919
overall_status: COMPLETED
sponsor: Vitkovice Hospital
study_type: OBSERVATIONAL
primary_condition: Colorectal Cancer
countries: Czechia
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01478919.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01478919"
ct_last_update_post_date: 2013-09-20
last_seen_at: "2026-05-12T07:17:11.085Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Risk Factors for Residual Neoplasia After Endoscopic Mucosal Resection

**Official Title:** Risk Factors for Local Residual Neoplasia After Convetional Endoscopic Mucosal Resection of Laterally Spreading Tumors

**NCT ID:** [NCT01478919](https://clinicaltrials.gov/study/NCT01478919)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 127
- **Lead Sponsor:** Vitkovice Hospital
- **Conditions:** Colorectal Cancer
- **Start Date:** 2010-01
- **Completion Date:** 2011-11
- **CT.gov Last Update:** 2013-09-20

## Brief Summary

Laterally Spreading Tumors (LST) are important precursosrs of invasive colorectal cancer. Endoscopic treatment has replaced surgery in most of the cases. Nevertheless, after conventional Endoscopic Mucosal Resection (CER), Local Residual Neoplasia (LRN) is an issue. Therefore, endoscopic follow-up and treatment are necessary. To decrease its occurrence, the risk factors of LRN shoudl be identified. Thereafter, in high-risk patients, other modalities of initial treatment including Endoscopic Submucosal Dissection (ESD) and surgical treatment, could be considered. The purpose of this prospective study is to identify risk factors associated with the presence of LRN after CER of LSTs.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* all consecutive patients referred for EMR of LST

Exclusion Criteria:

* polyposis syndromes
* previous therapeutic attempt
```

## Primary Outcomes

- **Occurence of Local Residual Neoplasia (LRN)** _(time frame: 3 months)_ — LRN was defined as a histologically confirmed neoplastic tissue in the biopsy samples obtained from post-resection scar during follow-up colonoscopy 3 months after endoscopic resection

## Secondary Outcomes

- **Evaluation of Selected Risk Factors for Local Residual Neoplasia (LRN)** _(time frame: 3 months)_

## Locations (1)

- Vitkovice Hospital, Ostrava, Czechia

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.vitkovice hospital|ostrava||czechia` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT01478919.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT01478919*  
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