---
title: Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors
nct_id: NCT01692873
overall_status: COMPLETED
phase: NA
sponsor: Institut Paoli-Calmettes
study_type: INTERVENTIONAL
primary_condition: Pancreatic Tumor
countries: France
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01692873.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01692873"
ct_last_update_post_date: 2026-04-21
last_seen_at: "2026-05-12T07:05:05.785Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors

**Official Title:** Research for Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors - PACAomics / IPC 2011-004

**NCT ID:** [NCT01692873](https://clinicaltrials.gov/study/NCT01692873)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 274
- **Lead Sponsor:** Institut Paoli-Calmettes
- **Conditions:** Pancreatic Tumor
- **Start Date:** 2012-02
- **Completion Date:** 2017-12
- **CT.gov Last Update:** 2026-04-21

## Brief Summary

Pancreatic cancer is among the most serious human neoplasia and the most difficult to treat.

Most patients present at diagnosis a non resectable, locally advanced or metastatic disease, with a median survival of 12 month.

The aim of this study is the identification of diagnosis biomarkers, predictive of the therapeutic response.

This project investigate the use of molecular analyses applied to pancreatic tumor cells collected by microbiopsy under ultrasound-endoscopy, and blood cells.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Suspicion of pancreatic adenocarcinoma
* Patient \> 18 years old
* Social Security affiliation
* Signed informed consent

Exclusion Criteria:

* Patient in emergency situation
* Major person being the object of a legal protective measure or unable to express its consent
```

## Arms

- **suspected pancreatic tumor** (EXPERIMENTAL) — Realization of pancreatic tumor biopsy and blood samples

## Interventions

- **suspected pancreatic tumor** (PROCEDURE) — Realization of pancreatic surgery to obtain tumor biopsy and blood samples to realize biomarkers analyses.

## Primary Outcomes

- **Biomarkers** _(time frame: within twenty four hours)_ — Genomics, transcriptomics and proteomics analyses to determine presence or absence of biomarkers

## Secondary Outcomes

- **Histology** _(time frame: within twenty four hours)_

## Locations (1)

- Marine GILABERT, MD, Marseille, France

## Recent Field Changes (last 30 days)

- `results.hasResults` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `locations.marine gilabert, md|marseille||france` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT01692873.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT01692873*  
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