---
title: "Implementation of a Rapid Recovery Program in Gynecologic Oncology Surgery: A Pilot Study"
nct_id: NCT01705288
overall_status: COMPLETED
phase: EARLY_PHASE1
sponsor: Masonic Cancer Center, University of Minnesota
study_type: INTERVENTIONAL
primary_condition: Cervical Cancer
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01705288.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01705288"
ct_last_update_post_date: 2020-02-17
last_seen_at: "2026-05-12T07:01:21.350Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Implementation of a Rapid Recovery Program in Gynecologic Oncology Surgery: A Pilot Study

**NCT ID:** [NCT01705288](https://clinicaltrials.gov/study/NCT01705288)

## Key Facts

- **Status:** COMPLETED
- **Phase:** EARLY_PHASE1
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 103
- **Lead Sponsor:** Masonic Cancer Center, University of Minnesota
- **Conditions:** Cervical Cancer, Uterine Endometrial Cancer, Ovarian Cancer
- **Start Date:** 2013-01-01
- **Completion Date:** 2016-08-24
- **CT.gov Last Update:** 2020-02-17

## Brief Summary

Over 600,000 hysterectomies are performed annually in the United States. Despite increasing use of less invasive approaches, the majority of hysterectomies are still performed via traditional laparotomy, which can be associated with generally slower recovery and longer lengths of post-operative hospitalization. Rapid Recovery Protocols (RRP) seek to optimize post-surgical morbidity outcomes by returning a patient to normal physiology as quickly as possible following surgery.

## Detailed Description

Subjects will be randomly assigned to one of two groups: Rapid recovery protocol (regional anesthesia, pain control options with emphasis on nonsteroidal anti-inflammatory drugs (NSAIDS) over narcotic pain medications, early ambulation, and early enteral feeding) or standard of care (traditional laparatomy and supportive care).

## Eligibility

- **Minimum age:** 19 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Women who are being seen at the Women's Health Center by the Gynecologic Oncology group at the University of Minnesota if planned surgery includes an exploratory laparotomy

Exclusion Criteria:

* \< 19 years old
* Pregnant
* Undergoing a procedure other than laparotomy
* Scheduled to be discharged the same day of surgery
* Chronic narcotic pain medication user
* American Society of Anesthesiologists (ASA) score of \> or = 3
* Any condition that would exclude women from undergoing regional anesthesia
```

## Arms

- **Control Group (Standard Laparotomy)** (ACTIVE_COMPARATOR) — Patients undergoing standard anesthesia and standard exploratory laparotomy. Treatment will be per your surgeon's routine standards.
- **Rapid Recovery Group** (EXPERIMENTAL) — Protocol for "rapid recovery laparotomy" procedure involves pre-operative counseling, the use of regional anesthesia (spinal or epidural pain management rather than intravenous narcotics), post-operative use of non-steroidal anti-inflammatory drugs, early eating after surgery, early walking, and certain goals for discharge from the hospital.

## Interventions

- **Laparotomy** (PROCEDURE) — Exploratory surgery for gynecologic diagnosis.Involves pre-operative counseling, the use of regional anesthesia (spinal or epidural pain management rather than intravenous narcotics), early eating after surgery, early walking, and certain goals for discharge from the hospital
- **intravenous narcotics** (DRUG) — given for pain management after surgery per physician orders
- **standard anesthesia** (DRUG) — inhalant or intravenous during surgery
- **regional anesthesia** (DRUG) — given by spinal or epidural infusion
- **Non-steroidal anti-inflammatory drugs** (DRUG) — given for pain management after surgery

## Primary Outcomes

- **Hospital Stay** _(time frame: 1 Month)_ — Length of hospital stay for patients undergoing laparotomy on the gynecologic oncology service measured as whole days from the day of surgery until discharge

## Secondary Outcomes

- **Pain Medications Used** _(time frame: Post operative - day 2)_
- **Pain Assessment** _(time frame: Day 0)_

## Locations (1)

- Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States

## Recent Field Changes (last 30 days)

- `outcomes.secondary` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.masonic cancer center, university of minnesota|minneapolis|minnesota|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT01705288.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT01705288*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*