---
title: To Study the Effect of Organic Light Emitting Diodes (OLED) on Cultured Fibroblast
nct_id: NCT01724710
overall_status: UNKNOWN
sponsor: National Taiwan University Hospital
study_type: OBSERVATIONAL
primary_condition: Non-pressure Chronic Ulcer of Skin, Not Elsewhere Classified
countries: Taiwan
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01724710.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01724710"
ct_last_update_post_date: 2012-11-12
last_seen_at: "2026-05-12T06:08:01.285Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# To Study the Effect of Organic Light Emitting Diodes (OLED) on Cultured Fibroblast

**NCT ID:** [NCT01724710](https://clinicaltrials.gov/study/NCT01724710)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 10
- **Lead Sponsor:** National Taiwan University Hospital
- **Conditions:** Non-pressure Chronic Ulcer of Skin, Not Elsewhere Classified
- **Start Date:** 2012-08
- **CT.gov Last Update:** 2012-11-12

## Brief Summary

Chronic ulcers is a common clinical problem. Diabetes or peripheral vascular occlusion is major reason leading to chronic wound healing.

The investigators's previous animal experiments have confirmed that OLED can promote burn wound healing and fibroblast proliferation in normal Wistar rat.

In order to find the time point and dosage of the effective light therapy. The investigators further use cultured human fibroblasts in vitro to study light therapy to promote fibroblast proliferation mechanisms.

Expect clinical application of light therapy in the future is more accurate and effective.

## Detailed Description

Chronic ulcers is a common clinical problem. Diabetes or peripheral vascular occlusion is major reason leading to chronic wound healing.

Therapeutic methods to promote wound healing are hyperbaric oxygen therapy, vacuum assisted therapy and photostimulation.

Although there are many treatments but no one has been widely accepted. The clinical effects of uncertainty, high cost and inconvenience of use is the main reason.

Each year amputation of the population due to chronic ulcers has not decreased. In order to break the current medical difficulties, We refer to the new light therapy technology.

Look forward to shorten the healing time and reduce medicine costs. The investigators's previous animal experiments have confirmed that OLED can promote burn wound healing and fibroblast proliferation in normal Wistar rat.

In order to find the time point and dosage of the effective light therapy. The investigators further use cultured human fibroblasts in vitro to study light therapy to promote fibroblast proliferation mechanisms.

Expect clinical application of light therapy in the future is more accurate and effective irradiative time points and dosage.

## Eligibility

- **Minimum age:** 50 Years
- **Maximum age:** 80 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* chronic ulcer
* normal skin
* age 50\~80 years,
* chronic skin ulcer patient
* skin-grafting patient

Exclusion Criteria:
```

## Arms

- **chronic ulcer** — 1x1cm2 tissue from chronic ulcer wound
- **normal skin** — 1x1x0.1 cm3 normal skin from graft

## Locations (1)

- National Taiwan University Hospital, Taipei, Taiwan — _RECRUITING_

## Recent Field Changes (last 30 days)

- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `locations.national taiwan university hospital|taipei||taiwan` — added _(2026-05-12)_

---

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*Source data (authoritative): https://clinicaltrials.gov/study/NCT01724710*  
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