---
title: Perforator Artery Changes During Suprafascial Pre-expansion of the Perforator Flaps
nct_id: NCT01777386
overall_status: COMPLETED
phase: NA
sponsor: Istanbul University
study_type: INTERVENTIONAL
primary_condition: Scar
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01777386.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01777386"
ct_last_update_post_date: 2013-01-29
last_seen_at: "2026-05-12T07:04:21.014Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Perforator Artery Changes During Suprafascial Pre-expansion of the Perforator Flaps

**NCT ID:** [NCT01777386](https://clinicaltrials.gov/study/NCT01777386)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 14
- **Lead Sponsor:** Istanbul University
- **Conditions:** Scar, Contracture, Flap Disorder
- **Start Date:** 2009-06
- **Completion Date:** 2013-01
- **CT.gov Last Update:** 2013-01-29

## Brief Summary

Tissue expansion methods have been recommended as a means of improving the clinical results with perforator flaps but in plastic surgery literature there are few clinical trials supporting this opinion. The purposes of this clinical study are to address the ''preexpanded perforator flap concept'' by demonstrating a case series of relevant reconstructive procedures and to evaluate the perforator vessel changes that happen during the expansion periods of various perforator flap donor sites.

## Eligibility

- **Minimum age:** 6 Years
- **Maximum age:** 60 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* patients with broad scars and contracture bands
* patients with esophagocutaneous fistula
* patients with ambiguous genitalia

Exclusion Criteria:

* none
```

## Arms

- **preexpanded flap** (ACTIVE_COMPARATOR) — Fourteen patients were treated with fifteen '' preexpanded perforator flap surgery '' interventions. The last six cases were evaluated in terms of perforator artery diameter before and after expansion process. The preexpanded flap donor sites' perforator artery diameters were also compared with their anatomic equivalents located in the symmetric side of the body.
- **control side** (NO_INTERVENTION) — In six of the 14 patients, perforator artery diameter of the nonexpanded symmetric anatomical side of the body (equivalent to the expanded site)were measured.

## Interventions

- **preexpanded perforator flap surgery** (PROCEDURE)

## Primary Outcomes

- **Transferred tissue dimensions** _(time frame: At least five months after the operation)_ — Demonstrating the amount of transferred healthy tissue exhibits the success of the technique.

## Secondary Outcomes

- **Diameter of the perforator artery in a particular tissue level** _(time frame: Measured the day before the expander implantation surgery and the day before the flap transfer surgery (second session following tissue expansion))_

## Recent Field Changes (last 30 days)

- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT01777386.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT01777386*  
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