---
title: Saphenous Vein Cannulation in Infants and Small Children
nct_id: NCT01924975
overall_status: COMPLETED
phase: NA
sponsor: Satoshi Hanada
study_type: INTERVENTIONAL
primary_condition: Saphenous Vein Cannulation
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT01924975.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT01924975"
ct_last_update_post_date: 2018-01-23
last_seen_at: "2026-05-12T06:28:09.185Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Saphenous Vein Cannulation in Infants and Small Children

**Official Title:** Ultrasound-image Guided Versus Traditional Landmark Technique for Saphenous Vein Cannulation in Infants and Small Children

**NCT ID:** [NCT01924975](https://clinicaltrials.gov/study/NCT01924975)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 102
- **Lead Sponsor:** Satoshi Hanada
- **Conditions:** Saphenous Vein Cannulation
- **Start Date:** 2013-07
- **Completion Date:** 2014-07
- **CT.gov Last Update:** 2018-01-23

## Brief Summary

The purpose of this study is to compare the two different saphenous vein cannulation techniques; real-time ultrasound image-guided technique (Ultrasound group) vs. traditional landmark technique (Landmark group).

## Eligibility

- **Maximum age:** 4 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

1. Pediatric patient undergoing scheduled surgery which requires venous cannulation.
2. Term neonates and children \< 4 years old weighing \>/= 3 kg

Exclusion Criteria:

1. Patient with visible saphenous vein
2. Patient with no detectable saphenous vein under ultrasound
3. Patient with a skin wound or infection around puncture site
4. Patient with recent venous puncture at the puncture site (less than 1 month)
5. Patient with thrombus in saphenous vein or hematoma formation around the vein detected by ultrasound.
6. Patient with any emergency surgery
```

## Arms

- **Landmark group** (ACTIVE_COMPARATOR) — An operator is not allowed to use an ultrasound. A 22 or 24 G catheter will be advanced blindly toward the expected location of the saphenous vein at the level of the medial malleolus. Once blood appears in the hub, then the catheter will be advanced into the saphenous vein.
- **Ultrasound group** (ACTIVE_COMPARATOR) — An operator will identify the saphenous vein by using ultrasound with a linear transducer (L15-7io) in short axis view. A 22 or 24 G catheter will be advanced until the tip of the needle is seen on the ultrasound image. The needle is then advanced until blood appears in the hub. The catheter is then advanced into the saphenous vein.

## Interventions

- **Saphenous vein cannulation** (PROCEDURE) — Intravenous cannulation to saphenous vein
- **ultrasound with a linear transducer (L15-7io)** (DEVICE) — Portable, bed-side ultrasound to detect saphenous vein
- **A 22 or 24 G intravenous catheter** (DEVICE)

## Primary Outcomes

- **Percentage of Participants With First Attempt Success of Saphenous Vein Cannulation** _(time frame: 10 minutes)_

## Secondary Outcomes

- **Percentage of Participants With Success of Saphenous Vein Cannulation Within 3 Attempts of Needle Insertion, or a 10 Minute Time Period.** _(time frame: 10 minutes)_
- **Time Required for Overall Successful Venous Cannulation.** _(time frame: 10 minutes)_

## Locations (1)

- University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.university of iowa hospitals & clinics|iowa city|iowa|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT01924975.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT01924975*  
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