---
title: Effects of Panax Ginseng and Salvia Miltiorrhiza Supplementation on Vascular Function
nct_id: NCT02007304
overall_status: UNKNOWN
phase: NA
sponsor: National Taiwan University Hospital
study_type: INTERVENTIONAL
primary_condition: Healthy
countries: Taiwan
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT02007304.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02007304"
ct_last_update_post_date: 2013-12-10
last_seen_at: "2026-05-12T06:41:12.970Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Effects of Panax Ginseng and Salvia Miltiorrhiza Supplementation on Vascular Function

**Official Title:** Effects of Panax Ginseng and Salvia Miltiorrhiza Supplementation on Preventing Arterial Stiffening Effects Induced by Acute and Chronic Eccentric Exercise

**NCT ID:** [NCT02007304](https://clinicaltrials.gov/study/NCT02007304)

## Key Facts

- **Status:** UNKNOWN
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 48
- **Lead Sponsor:** National Taiwan University Hospital
- **Conditions:** Healthy
- **Start Date:** 2012-11
- **CT.gov Last Update:** 2013-12-10

## Brief Summary

The purpose of is to determine the preventive effects of Chinese herb supplement with panax ginseng and salvia miltiorrhiza prior to eccentric resistance exercise on arterial stiffness and vascular reactivity by using a double-blind randomized control design and to examine the effects of a 12-week progressive eccentric resistance exercise training on arterial elasticity and vascular reactivity, and whether a long-term supplementation would ameliorate arterial stiffening effects elicited by exercise-induced inflammation and improve endothelial function.

## Eligibility

- **Minimum age:** 20 Years
- **Maximum age:** 60 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

-Healthy sedentary adults

Exclusion Criteria:

* obesity (BMI \>30 kg/m2)
* smoking within past six months
* hypertension (high blood pressure \>140/90 mmHg)
* personal history of diabetes (fasting blood glucose \>126 mg/dL), heart disease, or other cardiovascular problems
* orthopedic injury that may prevent him or her from completing the exercise
* the use of over-the-counter supplements or vitamins
```

## Arms

- **Herbs** (EXPERIMENTAL) — participants assigned to experimental arm will take 300mg panax ginseng and 300mg salvia miltiorrhiza extracts in capsules for 12 weeks along with eccentric exercise training
- **Placebo** (PLACEBO_COMPARATOR) — parcipants in this group will take placebo capsule containing microcrystalline cellulose

## Interventions

- **Eccentric exercise training** (BEHAVIORAL) — 12 weeks of lower leg eccentric training

## Primary Outcomes

- **Pulse Wave Velocity** _(time frame: Before eccentric exercise and training)_ — PWV will be measured before, 6th week, 12th week of eccentric exercise training.
- **Pulse Wave Velocity** _(time frame: 6th week of eccentric exercise traininig)_ — PWV will be measured before, 6th week, 12th week of eccentric exercise training.
- **Pulse Wave Velocity** _(time frame: 12th week of eccentric exercise training)_ — PWV will be measured before, 6th week, 12th week of eccentric exercise training.

## Secondary Outcomes

- **Blood pressure** _(time frame: Before intervention)_
- **Blood pressure** _(time frame: 6th week of intervention)_
- **Blood pressure** _(time frame: 12th week of intervention)_

## Locations (1)

- National Taiwan University, Taipei, Taiwan — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.national taiwan university|taipei||taiwan` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT02007304.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT02007304*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*