---
title: Novel MRI Techniques in the Evaluation of Pulmonary Vascular Disease
nct_id: NCT02026531
overall_status: COMPLETED
phase: PHASE1, PHASE2
sponsor: Sheffield Teaching Hospitals NHS Foundation Trust
study_type: INTERVENTIONAL
primary_condition: Pulmonary Hypertension
countries: United Kingdom
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT02026531.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02026531"
ct_last_update_post_date: 2015-09-30
last_seen_at: "2026-05-12T06:24:42.285Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Novel MRI Techniques in the Evaluation of Pulmonary Vascular Disease

**NCT ID:** [NCT02026531](https://clinicaltrials.gov/study/NCT02026531)

## Key Facts

- **Status:** COMPLETED
- **Phase:** PHASE1, PHASE2
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 9
- **Lead Sponsor:** Sheffield Teaching Hospitals NHS Foundation Trust
- **Collaborators:** University of Sheffield
- **Conditions:** Pulmonary Hypertension
- **Start Date:** 2010-11
- **Completion Date:** 2015-09
- **CT.gov Last Update:** 2015-09-30

## Brief Summary

The diagnosis of a patient with pulmonary hypertension (PH) requires many investigations. At present cardiac catheterisation is the cornerstone investigation in these patients where it is used to establish disease severity and estimate prognosis. It is an invasive procedure which is expensive and not without risk to the patient. Despite the multitude of tests performed, identifying those patients with PH who have a poor diagnosis can be difficult. The aim of this study is to improve the assessment of patients with PH using novel magnetic resonance techniques.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* All cases referred to the clinic for assessment for possible pulmonary hypertension.

Exclusion Criteria:

* patients with a cardiac pacemaker or retained temporary pacing wire
* patients with aneurysm clip
* non MRI compatible heart valve prosthesis
* intra orbital metalic foreign body
* pregnancy
* metal prosthesis/spinal rods
* retained shrapnel
* cochlear implants/bladder stimulator
```

## Arms

- **3-Helium inhalation gas** (EXPERIMENTAL) — This is a pilot study. The aim is to recruit 20 patients who will all receive the product under investigation.

## Interventions

- **3-Helium gas** (OTHER) — 3-Helium gas for MRI contrast

## Primary Outcomes

- **pulmonary artery diameter (mm)** _(time frame: up to 3 months)_ — Three-dimensional MRI imaging will be used to acquire cardiac dimensions and anatomical ventilation distribution as well as regional partial pressures of oxygen in the lungs.

## Locations (1)

- Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, South Yorkshire, United Kingdom

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.sheffield pulmonary vascular disease unit, royal hallamshire hospital|sheffield|south yorkshire|united kingdom` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT02026531.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT02026531*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*