---
title: Impact of Staphylococcus Aureus on Folliculitis Decalvans
nct_id: NCT02157688
overall_status: COMPLETED
sponsor: Assistance Publique - Hôpitaux de Paris
study_type: OBSERVATIONAL
primary_condition: Folliculitis Decalvans
countries: France
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT02157688.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02157688"
ct_last_update_post_date: 2016-06-24
last_seen_at: "2026-05-12T06:15:14.385Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Impact of Staphylococcus Aureus on Folliculitis Decalvans

**Official Title:** Role of Staphylococcus Aureus on Folliculitis Decalvans. A Comparative Bacteriological Study.

**NCT ID:** [NCT02157688](https://clinicaltrials.gov/study/NCT02157688)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 40
- **Lead Sponsor:** Assistance Publique - Hôpitaux de Paris
- **Conditions:** Folliculitis Decalvans, Staphylococcus Aureus
- **Start Date:** 2014-03
- **Completion Date:** 2015-03
- **CT.gov Last Update:** 2016-06-24

## Brief Summary

The folliculitis decalvans (FD) is an orphan disease , common in consultation specialized on scalp. This disease is currently not curable, responsible for significant for patients. The pathophysiology is poorly understood, Staphylococcus aureus (SA) appears to play a role, never previously studied, and the study will attempt to clarify it.

Controversies in the literature on the pathophysiological hypotheses can be summed up as follows :

FD is it an infectious folliculitis where SA (almost always found on the lesions plays a direct role possibly aided by a lack of local immune protection , or is it a pustular inflammatory unknown cause where the SA has no direct role but is a cofactor or a simple germ superinfection.

Our study has plans to bring new evidence to help decide between these two opposite but not mutually exclusive concepts .

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Adult (\>18 yo)
* Alopecia
* folliculitis decalvans
* At least 6 months of evolution
* no antibiotics
* presence of pustules and crusts
* Adult (\>18 yo)

Exclusion Criteria:

* immunosuppression
* pregnancy
```

## Arms

- **case** — Patient with a folliculitis Decalvans
- **control** — Control without folliculitis decalvans

## Interventions

- **no intervention : case control study** (OTHER)

## Primary Outcomes

- **presence of Staphylococcus Aureus in cutaneous biopsies (at least one colony)** _(time frame: 1 day)_ — The primary endpoint is the presence of Staphylococcus Aureus in cutaneous biopsies before any therapy and notably antibiotics.

## Secondary Outcomes

- **presence of Staphylococcus Aureus in cutaneous biopsies (at least one colony) after treatment** _(time frame: 10 weeks)_
- **presence of Staphylococcus Aureus in nasal swab (at least one colony)** _(time frame: 1 day)_

## Locations (1)

- Saint-Louis Hospital, Paris, Paris, France

## Recent Field Changes (last 30 days)

- `design.enrollmentCount` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.saint-louis hospital|paris|paris|france` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT02157688.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT02157688*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*