---
title: "Relationship of Essential Hypertension and Its Treatments on the Postoperative Pain Management: a Prospective, Observational, Cross-sectional Study"
nct_id: NCT02244177
overall_status: UNKNOWN
sponsor: Kaohsiung Veterans General Hospital.
study_type: OBSERVATIONAL
primary_condition: Hypertension
countries: Taiwan
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT02244177.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02244177"
ct_last_update_post_date: 2015-04-01
last_seen_at: "2026-05-12T06:27:53.585Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Relationship of Essential Hypertension and Its Treatments on the Postoperative Pain Management: a Prospective, Observational, Cross-sectional Study

**NCT ID:** [NCT02244177](https://clinicaltrials.gov/study/NCT02244177)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 300
- **Lead Sponsor:** Kaohsiung Veterans General Hospital.
- **Conditions:** Hypertension
- **Start Date:** 2013-11
- **CT.gov Last Update:** 2015-04-01

## Brief Summary

Numbers of postoperative PCA related side effects among three groups will be determined by comparing and analyzing frequency distributions. To determine whether the patients with hypertension require less post operative opiate analgesics than others, multivariate analysis with repeated measures will be performed to identify the major and the minor factors predicting the use of postoperative pain therapy. The major aim of the study is to test the hypothesis that the morphine comsumpted by the hypertension group is less than those of the normotension group. The minor aims for the study are the difference related to pain intensity, or the incidence of side effects among groups.

## Eligibility

- **Minimum age:** 20 Years
- **Maximum age:** 75 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* 300 eligible subjects
* No contraindication for inhalation anesthesia
* Elective surgery
* Age between 20-75 y/o
* No contraindication for postoperative morphine pain control
* Female or male
* Essential hypertension stage I and II (140\<=SBP\<=180; 90\<=DBP\<=110)

Exclusion Criteria:

* Liver disease
* Renal disease
* Those who is presumed to go to ICU after surgery
* The patients with dementia or conscious disturbance
* Pregnancy or breast feeding
* Secondary hypertension
* events in recent 6 months myocardial infarction cardiac bypass surgery unstable angina cerebrovascular events congestive heart failure significant arrhythmia thoracic surgery
```

## Arms

- **normotension group** — Until 11,March, 2015, 31 cases are collected.
- **hypertension group without treatment** — Until 11,March, 2015, 60 cases are collected.
- **hypertension group with antihypertensive treatment** — (ACEI, beta-blocker, Ca blocker, Diuretics) prior to the surgery.

Until 11,March, 2015, 59 cases are collected.

## Primary Outcomes

- **Pain** _(time frame: Post-operation Day1 to Day4)_

## Secondary Outcomes

- **Morphine consumption** _(time frame: Post-operation Day1 to Day4)_

## Locations (1)

- Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.kaohsiung veterans general hospital|kaohsiung city||taiwan` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT02244177.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT02244177*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*