---
title: Clinical Observation of Coronary Arterial Microcirculation Dysfunction in Diabetic Patients With Non- Obstructive Coronary Artery Disease
nct_id: NCT02748980
overall_status: UNKNOWN
sponsor: "Shaanxi Provincial People's Hospital"
study_type: OBSERVATIONAL
primary_condition: Complications of Diabetes Mellitus
countries: China
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT02748980.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02748980"
ct_last_update_post_date: 2016-04-22
last_seen_at: "2026-05-12T06:12:48.285Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Clinical Observation of Coronary Arterial Microcirculation Dysfunction in Diabetic Patients With Non- Obstructive Coronary Artery Disease

**NCT ID:** [NCT02748980](https://clinicaltrials.gov/study/NCT02748980)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 200
- **Lead Sponsor:** Shaanxi Provincial People's Hospital
- **Conditions:** Complications of Diabetes Mellitus, Coronary Artery Disease
- **Start Date:** 2016-03
- **CT.gov Last Update:** 2016-04-22

## Brief Summary

The purpose of this study is to investigate the prevalence and degree of coronary arterial microcirculaiton dysfunction of non- obstructive coronary artery disease in patients with type 2 diabetes. Furthermore, the risk factors of coronary arterial microcirulation would be screened and identified.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 80 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Diagnosis non- obstructive coronary artery disease;
* Positive Treadmill exercise test;
* Positive Cardiac ECT test;
* Positive Holter test

Exclusion Criteria:

* Diagnosis of myocardial infarction;
* Diagnosis heart failure;
* Diagnosis of chronic kidney disease;
* Diagnosis of heart valvular disease;
* Diagnosis of malignant tumor;
* Positive heart transplant history;
* Pregnant and lactating women
```

## Arms

- **Non- obstructive coronary artery disease, non- diabetic** — Clinical evidences such as Holter, Treadmill exercise test and cardiac ECT support myocardial ischemia. CAG showed 20%-70% arterial stenosis. Patients are diagnosed without diabetes.
- **Non- obstructive coronary artery disease, diabetic** — Clinical evidences such as Holter, Treadmill exercise test and cardiac ECT support myocardial ischemia. CAG showed 20%-70% arterial stenosis. Patients are diagnosed with type 2 diabetes.

## Primary Outcomes

- **The coronary microcirculation dysfunction is measured by index of microcirculatory resistance** _(time frame: 10 minutes after diagnosis is made by CAG)_

## Locations (1)

- Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.shaanxi provincial people's hospital|xi'an|shaanxi|china` — added _(2026-05-12)_

---

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*Source data (authoritative): https://clinicaltrials.gov/study/NCT02748980*  
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