---
title: Driving Pressure and Postoperative Pulmonary Complications
nct_id: NCT02851238
overall_status: COMPLETED
phase: NA
sponsor: Samsung Medical Center
study_type: INTERVENTIONAL
primary_condition: One-Lung Ventilation
countries: South Korea
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT02851238.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02851238"
ct_last_update_post_date: 2018-10-09
last_seen_at: "2026-05-12T06:43:48.885Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Driving Pressure and Postoperative Pulmonary Complications

**Official Title:** Driving Pressure Limited Ventilation Decreases Postoperative Pulmonary Complications in One-Lung Ventilation: Randomized Controlled Study

**NCT ID:** [NCT02851238](https://clinicaltrials.gov/study/NCT02851238)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 312
- **Lead Sponsor:** Samsung Medical Center
- **Conditions:** One-Lung Ventilation, Postoperative Respiratory Complications, Driving Pressure
- **Start Date:** 2016-08-12
- **Completion Date:** 2017-09-01
- **CT.gov Last Update:** 2018-10-09

## Brief Summary

This study aims to prove that driving pressure limited ventilation is superior in preventing postoperative pulmonary complications to existing protective ventilation.

## Eligibility

- **Minimum age:** 19 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Adults greater than or equal to 19 years
* Patient who undergoes one-lung ventilation for thoracic surgery

Exclusion Criteria:

* The American Society of Anesthesiologists (ASA) Physical Status classification greater than or equal to 4
* Patient who is contraindicated with application of positive end expiratory pressure
* Patient who rejects being enrolled in the study
```

## Arms

- **Protective Ventilation** (NO_INTERVENTION) — The control arm receives existing conventional protective ventilation with tidal volume of 6mL/kg of ideal body weight and positive end expiratory ventilation of 5cmH2O during one-lung ventilation
- **Driving Pressure Limited Ventilation** (EXPERIMENTAL) — The intervention arm receives driving pressure limited ventilation during one-lung ventilation

## Interventions

- **Driving Pressure Limited Ventilation** (OTHER) — Positive end expiratory pressure is adjusted to minimize driving pressure, plateau pressure minus end expiratory pressure from 2 to 10 cmH2O during one-lung ventilation

## Primary Outcomes

- **The incidence of postoperative pulmonary complications** _(time frame: within the first 3 days after surgery)_ — Patient is regarded to have postoperative pulmonary complication when 4 or more positive variables exists according to Melbourne Group Scale.

## Secondary Outcomes

- **Partial pressure of oxygen in arterial blood** _(time frame: during surgery)_
- **The ratio of partial pressure arterial oxygen and fraction of inspired oxygen** _(time frame: on the first postoperative day)_

## Locations (1)

- Samsung medical center, Seoul, South Korea

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.samsung medical center|seoul||south korea` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT02851238.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT02851238*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*