---
title: Incidence of Acute Kidney Injury After Laparoscopic Cholecystectomy
nct_id: NCT02873624
overall_status: TERMINATED
sponsor: Western Galilee Hospital-Nahariya
study_type: OBSERVATIONAL
primary_condition: Acute Kidney Injury ,Laparoscopic Cholecystectomy
countries: Israel
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT02873624.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02873624"
ct_last_update_post_date: 2019-06-12
last_seen_at: "2026-05-12T06:11:41.385Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Incidence of Acute Kidney Injury After Laparoscopic Cholecystectomy

**NCT ID:** [NCT02873624](https://clinicaltrials.gov/study/NCT02873624)

## Key Facts

- **Status:** TERMINATED
- **Why Stopped:** No patients recruited
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 100
- **Lead Sponsor:** Western Galilee Hospital-Nahariya
- **Conditions:** Acute Kidney Injury ,Laparoscopic Cholecystectomy
- **Start Date:** 2016-09
- **Completion Date:** 2018-12-31
- **CT.gov Last Update:** 2019-06-12

## Brief Summary

The aim of this study is to establish AKI incidence in patients who are undergoing laparoscopic cholecystectomy and to identify the potential risk factors associated with the development of AKI.

## Detailed Description

Introduction: Laparoscopic procedure produces adverse effects on splanchnic organs. Pneumoperitoneum is a non-physiologic condition that causes a higher intra-abdominal pressure (IAP) and is associated with significant direct and indirect effects on renal physiology.

Aim of the study:

To establish AKI incidence in patients who are undergoing laparoscopic cholecystectomy.

To identify the potential risk factors associated with the development of AKI. To establish the relationship between the IAP during the procedure and the AKI incidence.

Study Design:

Study population: A single center prospective cohort study will be conducted. 100 patients undergoing elective laparoscopic cholecystectomy in the Galilee Medical Center will be included.

Inclusion criteria: age \> 18 years, able to sign the consent form, stable kidney function.

Exclusion criteria: end stage renal disease, acute kidney injury or need of dialysis three months prior the procedure, acute infection, acute inflammation, BMI \> 40, malignancy and pregnancy.

The diagnosis of AKI will be made based on Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guideline 2012, by comparing the baseline and post-operative serum creatinine and cystatin C and monitoring urine output during the procedure and after the procedure for 24 hours.

Data Analysis: Results will be presented as mean ± standard deviation for quantitative data. A p value of \<0.05 will be considered statistically significant.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* age \> 18 years, able to sign the consent form, stable kidney function.

Exclusion Criteria:

* end stage renal disease
* acute kidney injury or need of dialysis three months prior the procedure
* acute infection
* acute inflammation
* malignancy
* pregnancy
```

## Interventions

- **Laparoscopic cholecystectomy** (PROCEDURE)

## Primary Outcomes

- **The incidence of AKI following a laparoscopic cholecystectomy** _(time frame: Up to one week after the procedure)_ — kidney function, included estimated GFR and urinary markers will be measured

## Locations (1)

- Western Galilee Hospital, Nahariya, Israel

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.whyStopped` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.western galilee hospital|nahariya||israel` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT02873624.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT02873624*  
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