---
title: Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation
nct_id: NCT03140748
overall_status: COMPLETED
phase: NA
sponsor: Centre Hospitalier Universitaire, Amiens
study_type: INTERVENTIONAL
primary_condition: Peritonitis Infectious
countries: France
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT03140748.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT03140748"
ct_last_update_post_date: 2025-09-19
last_seen_at: "2026-05-12T07:32:06.785Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation

**NCT ID:** [NCT03140748](https://clinicaltrials.gov/study/NCT03140748)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 70
- **Lead Sponsor:** Centre Hospitalier Universitaire, Amiens
- **Conditions:** Peritonitis Infectious, Candida Infection
- **Start Date:** 2018-05-01
- **Completion Date:** 2023-06-01
- **CT.gov Last Update:** 2025-09-19

## Brief Summary

Intraabdominal fungal infections with Candida are constantly increasing. Their diagnosis and treatment is difficult. Morbidity and mortality are high. Β-D-Glucan has been proposed as a marker of systemic fungal infection in candidemia. Moreover, its kinetics is associated with therapeutic success. On the other hand, there are no data on intraabdominal infections that are much more frequent. The objective of the study is to evaluate the initial levels of β-D-glucan and its daily kinetics during the treatment of fungal peritonitis in resuscitation compared to a control group with a yeast-free peritonitis.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Major Patient (age ≥ 18 years)
* Community or associated peritonitis, operated and hospitalized in resuscitation
* Affiliation to a social security scheme

Exclusion Criteria:

* Allergy known to echinocandins
* Dying Patient
* Limitation of care
* Predictable duration of follow-up ≤ 10 days
* Transfusion within 3 months
* Patient minor, patient under guardianship or curatorship
```

## Arms

- **Patients with fungal peritonitis** (OTHER)
- **Patients with peritonitis without yeast** (OTHER)

## Interventions

- **To evaluate the initial levels and kinetics of serum β-D-glucan** (OTHER) — To evaluate the initial levels and kinetics of serum β-D-glucan during fungal peritonitis compared to a control group of yeast-free peritonitis

## Primary Outcomes

- **Blood determination of serum β-D-glucan kinetics in patients with peritonitis** _(time frame: 28 days)_ — Blood determination of serum β-D-glucan kinetics in patients with peritonitis

## Locations (1)

- CHU Amiens Picardie, Amiens, Picardie, France

## Recent Field Changes (last 30 days)

- `design.enrollmentCount` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.chu amiens picardie|amiens|picardie|france` — added _(2026-05-12)_

---

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*Source data (authoritative): https://clinicaltrials.gov/study/NCT03140748*  
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