---
title: Comparison of Different Materials Contribution to Implants Stability
nct_id: NCT03501199
overall_status: COMPLETED
phase: NA
sponsor: Necmettin Erbakan University
study_type: INTERVENTIONAL
primary_condition: Dental Implant Failure Nos
countries: Turkey (Türkiye)
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT03501199.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT03501199"
ct_last_update_post_date: 2019-03-05
last_seen_at: "2026-05-12T06:36:58.985Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Comparison of Different Materials Contribution to Implants Stability

**Official Title:** Comparison of Different Materials Contribution to Immediate Implants Stability With Resonance Frequency Analysis

**NCT ID:** [NCT03501199](https://clinicaltrials.gov/study/NCT03501199)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 15
- **Lead Sponsor:** Necmettin Erbakan University
- **Conditions:** Dental Implant Failure Nos
- **Start Date:** 2018-03-01
- **Completion Date:** 2019-03-04
- **CT.gov Last Update:** 2019-03-05

## Brief Summary

The investigators will use two types of material(PRF-Xenograft) in the buccal gap after immediate dental implant placement. The study design has three groups PRF, graft, and control group. The patients will randomly be assigned to groups by envelop method. The resonance frequency analysis device(Osstell) will be used to measure primary and secondary stabilization. Then the investigators will evaluate each materials' contribution to stability.

Pre-op and 9th month Post-op CBCTs will evaluate about bone loss in mesial-distal and horizontal dimensions.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 60 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* medically healthy,
* only one maxillary aesthetic region(incisors or premolars) tooth which has two adjacent teeth is indicated for extraction.
* intact buccal socket walls
* the gap between buccal socket wall to implant sholder at least 2 mm.

Exclusion Criteria:

* relevant tooth has more than one root,
* smoking,
* alcohol abuse,
* pregnancy,
* immune-suppressive patients,
* any systemic disease.
```

## Arms

- **PRF Group** (EXPERIMENTAL) — PRF is will be used in immediate dental implant placement.
- **Graft Group** (EXPERIMENTAL) — The xenogenic graft is will be used in immediate dental implant placement.
- **Control Group** (EXPERIMENTAL) — No extra material is will be used in immediate dental implant placement.

## Interventions

- **platelet-rich fibrin placement** (OTHER) — filling the buccal gap with platelet-rich fibrin after immediate dental implant placement
- **xenogenic graft placement** (OTHER) — filling the buccal gap with xenogenic graft after immediate dental implant placement
- **no extra material** (OTHER) — filling the buccal gap with no material after immediate dental implant placement
- **tooth extraction** (PROCEDURE) — extraction of tooth which is unrestorable
- **immediate implant placement** (PROCEDURE) — putting dental implant into a socket which has been prepared with compatible drills
- **collagen membran placement** (OTHER) — placing collagen membran on extraction socket after dental implant placement to cover all
- **raising flap** (PROCEDURE) — raising the buccal flap with two vertical incision to cover extraction socket for primary closure

## Primary Outcomes

- **Primer Stabilization-Resonance Frequency Analysis** _(time frame: at 0 day)_ — initial measurement after placement by Osstell device

## Secondary Outcomes

- **Seconder Stabilization-Resonance Frequency Analysis** _(time frame: 120th day)_
- **Mesial-Distal and Horizontal Bone Loss** _(time frame: 9th month)_

## Locations (1)

- Necmettin Erbakan University, Faculty of dentistry, Konya, Turkey (Türkiye)

## Recent Field Changes (last 30 days)

- `design.phases` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.necmettin erbakan university, faculty of dentistry|konya||turkey (türkiye)` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT03501199.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT03501199*  
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