--- title: The Effect of Vitamin D and Exercise on Balance in Postmenopausal Women nct_id: NCT03608488 overall_status: COMPLETED phase: NA sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey study_type: INTERVENTIONAL primary_condition: Vitamin D Deficiency countries: Turkey (Türkiye) canonical_url: "https://parkinsonspathways.com/agent/trials/NCT03608488.md" clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT03608488" ct_last_update_post_date: 2020-07-01 last_seen_at: "2026-05-12T06:15:01.288Z" source: ClinicalTrials.gov (mirrored, no enrichment) --- # The Effect of Vitamin D and Exercise on Balance in Postmenopausal Women **NCT ID:** [NCT03608488](https://clinicaltrials.gov/study/NCT03608488) ## Key Facts - **Status:** COMPLETED - **Phase:** NA - **Study Type:** INTERVENTIONAL - **Target Enrollment:** 110 - **Lead Sponsor:** Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey - **Conditions:** Vitamin D Deficiency - **Start Date:** 2018-08-06 - **Completion Date:** 2019-07-12 - **CT.gov Last Update:** 2020-07-01 ## Brief Summary In recent years, skeletal and nonskeletal effects of vitamin D has been studied. One of the effects of it was balance and fall prevention. However, these studies were performed on older patients who had not vitamin D deficiency. This study aimed to evaluate the effect of vitamin D replacement therapy and exercise on balance in 50-70 years-old postmenopausal women. ## Eligibility - **Minimum age:** 50 Years - **Maximum age:** 70 Years - **Sex:** FEMALE - **Healthy Volunteers:** Yes ``` Inclusion Criteria: * 50-70 years-old postmenopausal women * Vitamin D level\<10 ng/ml and Vitamin D level\>30 ng/ml * Independant in daily life * Able to do exercise * Able to read and write in Turkish Exclusion Criteria: * Diabetes mellitus, * Polyneuropathy, * Spinal stenosis, * History of fracture or lower extremity operation, * Rheumatologic diseases, * History of chemotherapy * Cognitive impairment ``` ## Arms - **Vitamin D<10 ng/ml; Vitamin D replacement** (EXPERIMENTAL) — Vitamin D replacement (50.000 IU/per week, for 8 weeks) - **Vitamin D<10 ng/ml; Vitamin D replacement and exercise** (EXPERIMENTAL) — Vitamin D replacement (50.000 IU/per week, for 8 weeks) and Core and balance exercises for 8 weeks. - **Vitamin D<10 ng/ml; exercise** (EXPERIMENTAL) — Core and balance exercises for 8 weeks. - **Vitamin D>30ng/ml; exercise** (ACTIVE_COMPARATOR) — Core and balance exercises for 8 weeks. ## Interventions - **Vitamin D** (DIETARY_SUPPLEMENT) — Vitamin D3 50.000 IU/per week, for 8 weeks - **Exercise** (OTHER) — Core stability, balance exercises ## Primary Outcomes - **Postural Stability Test (Biodex) Assessed at Baseline** _(time frame: Baseline)_ — overall stability index: quantifying the ability to maintain dynamic postural stability The patient's score on this test assesses deviations from center, thus lower index means less instability and better balance. Measures were obtained from 20-sec trials during which participants were asked to maintain an upright standing position on their dominant limb on the unstable surface of the Biodex Stability and Balance System. 0 is the minimum score, but there is no defined maximum score - **Postural Stability Test (Biodex) Assessed After Treatment (8 Weeks)** _(time frame: After treatment (8 weeks))_ — overall stability index: quantifying the ability to maintain dynamic postural stability. The patient's score on this test assesses deviations from center, thus a lower score is more desirable than a higher score. Measures were obtained from 20-sec trials during which participants were asked to maintain an upright standing position on their dominant limb on the unstable surface of the Biodex Stability and Balance System 0 is the minimum score, but there is no defined maximum score - **Berg Balance Test Assessed at Baseline** _(time frame: Baseline)_ — 14-item scale designed to measure balance of the older adult in a clinical setting minimum: 0 maximum: 56 A score of 56 indicates functional balance. A score of \< 45 indicates individuals may be at greater risk of falling. - **Berg Balance Test Assessed After Treatment (8weeks)** _(time frame: After treatment (8 weeks))_ — 14-item scale designed to measure balance of the older adult in a clinical setting minimum: 0 maximum: 56 A score of 56 indicates functional balance. A score of \< 45 indicates individuals may be at greater risk of falling. ## Secondary Outcomes - **Fall Risk Assesment Performed at Baseline** _(time frame: Baseline)_ - **Fall Risk Assesment Performed After Treatment (8 Weeks)** _(time frame: After treatment (8 weeks))_ - **Health Status Assessed at Baseline** _(time frame: Baseline)_ - **Health Status Assessed After Treatment (8 Weeks)** _(time frame: After treatment (8 weeks))_ ## Locations (1) - Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey (Türkiye) ## Recent Field Changes (last 30 days) - `status.overallStatus` — added _(2026-05-12)_ - `status.primaryCompletionDate` — added _(2026-05-12)_ - `status.completionDate` — added _(2026-05-12)_ - `status.lastUpdatePostDate` — added _(2026-05-12)_ - `design.phases` — added _(2026-05-12)_ - `design.enrollmentCount` — added _(2026-05-12)_ - `eligibility.criteria` — added _(2026-05-12)_ - `eligibility.minAge` — added _(2026-05-12)_ - `eligibility.maxAge` — added _(2026-05-12)_ - `eligibility.sex` — added _(2026-05-12)_ - `outcomes.primary` — added _(2026-05-12)_ - `outcomes.secondary` — added _(2026-05-12)_ - `armsInterventions.arms` — added _(2026-05-12)_ - `armsInterventions.interventions` — added _(2026-05-12)_ - `sponsor.lead` — added _(2026-05-12)_ - `results.hasResults` — added _(2026-05-12)_ - `locations.sultan abdulhamid han training and research hospital|istanbul||turkey (türkiye)` — added _(2026-05-12)_ --- *Canonical: https://parkinsonspathways.com/agent/trials/NCT03608488.md* *Source data (authoritative): https://clinicaltrials.gov/study/NCT03608488* *This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*