---
title: Bilateral vs. Unilateral Erector Spinae Plane Block
nct_id: NCT03781687
overall_status: COMPLETED
phase: NA
sponsor: Kocaeli University
study_type: INTERVENTIONAL
primary_condition: Postoperative Pain
countries: Turkey (Türkiye)
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT03781687.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT03781687"
ct_last_update_post_date: 2019-11-25
last_seen_at: "2026-05-12T07:26:09.284Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Bilateral vs. Unilateral Erector Spinae Plane Block

**Official Title:** Bilateral vs. Unilateral Erector Spinae Plane Block for Laparoscopic Cholecystectomy; A Randomised Controlled Trial

**NCT ID:** [NCT03781687](https://clinicaltrials.gov/study/NCT03781687)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 90
- **Lead Sponsor:** Kocaeli University
- **Conditions:** Postoperative Pain, Cholecystitis; Gallstone
- **Start Date:** 2019-01-02
- **Completion Date:** 2019-06-29
- **CT.gov Last Update:** 2019-11-25

## Brief Summary

The importance of multimodal analgesia for postoperative pain management is well known and regional anesthesia techniques are commonly prefferred to provide better analgesia. Erector spinae plane block (ESB) is a new defined and effective regional anesthesia technique. But two injections can be unconfortable for some patients. With this study, we aimed to compare the analgesia effect of bilateral and unilateral ESP block for laparoscopic cholecystectomy.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 65 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* ASA I-II patients
* Pateints undergoing elective laparoscopic cholecystectomy

Exclusion Criteria:

* obesity (body mass index \>35 kg/m2)
* infection of the skin at the site of needle puncture area
* patients with known allergies to any of the study drugs
* coagulopathy
* recent use of analgesic drugs
```

## Arms

- **Bilateral** (ACTIVE_COMPARATOR) — Bilateral ESP block will be performed
- **Unilateral** (ACTIVE_COMPARATOR) — Unilateral ESP block will be performed

## Interventions

- **Bilateral ESP Block** (PROCEDURE) — Bilateral ESP Block will be performed at T8
- **Unilateral ESP Block** (PROCEDURE) — Unilateral ESP Block will be performed at T8 (right side)
- **Intravenous Morphine patient controlled analgesia device** (DEVICE) — 24 hour morphine consumption will be recorded

## Primary Outcomes

- **Morphine consumption** _(time frame: preoperative 24th hour)_ — Morphine consumption will be recorded

## Secondary Outcomes

- **Numeric Rating Scale** _(time frame: postoperative 24th hour)_

## Locations (1)

- Kocaeli University Hospital, İzmit, Kocaeli, Turkey (Türkiye)

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.kocaeli university hospital|i̇zmit|kocaeli|turkey (türkiye)` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT03781687.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT03781687*  
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