--- title: Source Monitoring Déficit in Neuropsychiatric Population nct_id: NCT03886584 overall_status: RECRUITING phase: NA sponsor: Hôpital le Vinatier study_type: INTERVENTIONAL primary_condition: Psychiatric Disorder countries: France canonical_url: "https://parkinsonspathways.com/agent/trials/NCT03886584.md" clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT03886584" ct_last_update_post_date: 2025-07-31 last_seen_at: "2026-05-12T06:41:15.685Z" source: ClinicalTrials.gov (mirrored, no enrichment) --- # Source Monitoring Déficit in Neuropsychiatric Population **NCT ID:** [NCT03886584](https://clinicaltrials.gov/study/NCT03886584) ## Key Facts - **Status:** RECRUITING - **Phase:** NA - **Study Type:** INTERVENTIONAL - **Target Enrollment:** 300 - **Lead Sponsor:** Hôpital le Vinatier - **Conditions:** Psychiatric Disorder - **Start Date:** 2019-03-08 - **Completion Date:** 2026-07-31 - **CT.gov Last Update:** 2025-07-31 ## Brief Summary the investigators will measure source-monitoring ability in patients with several neuropsychiatric condition and in healthy controls appaired in age, sex and educational level. Source-monitoring will be measured thanks to internal- and reality-monitoring informatic tasks.The investigators hypothesized patients with fronto-temporal abnormalities would show more marked deficits than patients with only frontal abnormalities. ## Detailed Description Source-monitoring abilities will be measured thanks to reality-monitoring testing (i.e. the ability to distinguish internal-generated events from external ones) and internal-monitoring testing (i.e. the ability to distinguish an imagined source from a performed one). A source-monitoring deficit have been demonstrated in patients with psychiatric conditions such as schizophrenia and seems linked to frontotemporal abnormalities (frontotemporal dysconnectivity and temporal hypoactivity). With a total of 150 patients, the investigators will include 30 patients per group: patients with pre-dementia stage Alzheimer, Alzheimer, Fronto-Temporal dementia, Lewy Body dementia or Parkinson and Bipolar Disorder, with the hypothesis that Bipolar Disorder patients will present less marked deficit. The investigators will recruit 150 healthy controls. ## Eligibility - **Minimum age:** 18 Years - **Maximum age:** 80 Years - **Sex:** ALL - **Healthy Volunteers:** Yes ``` Inclusion Criteria: * Subjects who gave their free and informed consent; * Men and women; * Aged 18 to 80; * Having normal or corrected vision; * Mastering the French language (read and spoken); * All subjects will not have a working memory deficit preventing the test from being passed (MMSE short version):AM patients should have a score of \