---
title: Distal Radial Artery Approach to Prevent Radial Artery Occlusion (DAPRAO)
nct_id: NCT04238026
overall_status: COMPLETED
phase: NA
sponsor: Instituto Nacional de Cardiologia Ignacio Chavez
study_type: INTERVENTIONAL
primary_condition: Radial Artery Occlusion
countries: Mexico
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04238026.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04238026"
ct_last_update_post_date: 2020-06-29
last_seen_at: "2026-05-12T07:32:43.485Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Distal Radial Artery Approach to Prevent Radial Artery Occlusion (DAPRAO)

**Official Title:** Distal Radial Artery Approach to Prevent Radial Artery Occlusion

**NCT ID:** [NCT04238026](https://clinicaltrials.gov/study/NCT04238026)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 282
- **Lead Sponsor:** Instituto Nacional de Cardiologia Ignacio Chavez
- **Conditions:** Radial Artery Occlusion
- **Start Date:** 2019-05-02
- **Completion Date:** 2020-03-31
- **CT.gov Last Update:** 2020-06-29

## Brief Summary

The main complication of transradial intervention is radial artery occlusion (RAO). This is relevant because it limits the radial approach for future interventions and disables this conduit for coronary bypass grafts and arteriovenous fistula. Observational studies suggest that distal radial access could reduce RAO incidence.

The primary endpoint of our study is to compare the efficacy of the distal and proximal transradial approaches in terms of RAO incidence. The safety endpoint is the incidence of complications between these two methods.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Perceptible radial artery pulse
* Diagnostic or interventional procedure feasible to be performed with radial access.

Exclusion Criteria:

* Myocardial infarction with ST segment elevation in time for primary angioplasty.
* Cardiogenic shock or hemodynamic instability.
* Clinical, plethysmography or ultrasound suggestive of occlusion of the radial artery
* Prior recent radial artery access (1 month)
```

## Arms

- **Distal radial artery approach** (EXPERIMENTAL) — Puncture in the snuff box area of the arm with through and through technique, advancement of a wire and placement of an hydrophilic sheath introducer.
- **Proximal radial artery approach** (ACTIVE_COMPARATOR) — Puncture in the ventral side of the arm (2 cm proximal to the styloid apophysis) with through and through technique, advancement of a wire and placement of an hydrophilic sheath introducer.

## Interventions

- **Distal radial artery approach** (PROCEDURE) — Use of distal radial artery approach in coronary angiography and angioplasty

## Primary Outcomes

- **The primary endpoint of our study is to compare the efficacy of the distal and proximal transradial approaches in terms of RAO incidence.** _(time frame: The RAO will be evaluated 24 hours after the procedure by ultrasound examination and was defined as the absence of both color pattern and pulsed wave registry.)_ — The primary endpoint of our study is to compare the efficacy of the distal and proximal transradial approaches in terms of RAO incidence.

## Locations (1)

- National Institute of Cardiology, Mexico City, Mexico

## Recent Field Changes (last 30 days)

- `locations.national institute of cardiology|mexico city||mexico` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT04238026.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT04238026*  
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