---
title: Persistent Postoperative Pain After Major Emergency Abdominal Surgery
nct_id: NCT04508465
overall_status: UNKNOWN
sponsor: Zealand University Hospital
study_type: OBSERVATIONAL
primary_condition: Chronic Postoperative Pain
countries: Denmark
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04508465.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04508465"
ct_last_update_post_date: 2020-09-09
last_seen_at: "2026-05-12T06:31:42.585Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Persistent Postoperative Pain After Major Emergency Abdominal Surgery

**NCT ID:** [NCT04508465](https://clinicaltrials.gov/study/NCT04508465)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 110
- **Lead Sponsor:** Zealand University Hospital
- **Conditions:** Chronic Postoperative Pain
- **Start Date:** 2020-06-04
- **Completion Date:** 2021-06-04
- **CT.gov Last Update:** 2020-09-09

## Brief Summary

Perioperative pain is one of the most significant complaints and problems for patients undergoing major open surgery. Pain after surgery carry an abundance of consequences such as reduced mobilization, reduced nutrition intake, reduced pulmonary capacity and increased risk of complications and length of hospitalization. The literature does not supply much information on short- or longer-term outcomes of pain treatment for emergency surgery. The investigators know that for planned surgery in general around 10-50 percentage suffer from persistent postoperative pain. It is therefore important to follow-up on the longer-term outcomes after the standardized analgesic pain treatment. Based on a predefined patient group called OMEGA (Optimizing Major EMergency Abdominal surgery) the investigators hypothesize that OMEGA patients will present a significant incidence rate of patients with persistent postoperative pain and/or continued opioid/non-opioid usage. Therefore this study is to investigate the incidence of prolonged postoperative pain and opioid/non-opioid consumption in OMEGA patients at 3 month after major emergency abdominal surgery.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* OMEGA patients (patients who have undergone major emergency abdominal surgery including the stomach, small or large bowel, or rectum for conditions such as perforation, ischemia, abdominal abscess, bleeding or obstruction)
* Age 18 or more
* Surgery performed within 72 hours of an acute admission or as an acute re-operation

Exclusion Criteria:

* Elective laparoscopy
* Diagnostic laparotomy/laparoscopy where no subsequent procedure is performed
* Non-elective hernia repair without bowel resection
* Admission or transfer to an intensive care unit
```

## Arms

- **OMEGA** — Patients who have undergone major emergency abdominal surgery including the stomach, small or large bowel, or rectum for conditions such as perforation, ischemia, abdominal abscess, bleeding or obstruction.

## Primary Outcomes

- **Pain Mobilization** _(time frame: Data is collected 3 months postoperative)_ — Pain during mobilization last week based on a self-made questionary
- **Opioids** _(time frame: Data is collected 3 months postoperative)_ — Daily opioid usage last week based on a self-made questionary

## Secondary Outcomes

- **Pain Rest** _(time frame: Data is collected 3 months postoperative)_
- **Non-opiod Analgesic** _(time frame: Data is collected 3 months postoperative)_
- **Barthel-20 Index** _(time frame: Data is collected 3 months postoperative)_
- **EuroQol-5** _(time frame: Data is collected 3 months postoperative)_
- **Montreal Cognitive Assessment test (Mini-MoCA)** _(time frame: Data is collected 3 months postoperative)_

## Locations (1)

- Zealand University Hospital, Department of Anaesthesiology, Køge, Denmark

## Recent Field Changes (last 30 days)

- `locations.zealand university hospital, department of anaesthesiology|køge||denmark` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT04508465.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT04508465*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*