---
title: Effects of Short Duration High-intensity Interval Training on Peak Oxygen Consumption
nct_id: NCT04656509
overall_status: COMPLETED
phase: NA
sponsor: University of Texas at Austin
study_type: INTERVENTIONAL
primary_condition: Cardiovascular Fitness
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04656509.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04656509"
ct_last_update_post_date: 2020-12-09
last_seen_at: "2026-05-12T07:23:38.985Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Effects of Short Duration High-intensity Interval Training on Peak Oxygen Consumption

**NCT ID:** [NCT04656509](https://clinicaltrials.gov/study/NCT04656509)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 11
- **Lead Sponsor:** University of Texas at Austin
- **Conditions:** Cardiovascular Fitness
- **Start Date:** 2019-04-01
- **Completion Date:** 2020-04-24
- **CT.gov Last Update:** 2020-12-09

## Brief Summary

High-intensity interval training (HIIT) is an effective tool to improve cardiovascular fitness and maximal anaerobic power. Different methods of HIIT have been studied but the effect of a maximal effort cycling and very short exercise time (i.e., 4-s) with short recovery time (15-30 s) and a high number of repetitions (i.e., 30 bouts) is unknown.

## Detailed Description

The investigators examined the effects of training at maximal anaerobic power during cycling (PC) on maximal anaerobic power, peak oxygen consumption (VO2peak), and total blood volume in 11 young healthy individuals (age: 21.3±0.5 y) (6 men, 5 women). Methods: Participants trained three times a week for eight weeks performing a PC program consisting of 30 bouts of 4-s at an all-out intensity (i.e., 2 minutes of exercise per session). The cardiovascular stress progressively increased over the weeks by decreasing the recovery time between sprints (30 to 24 to 15-s) and thus session time decreased from 17 to \< 10 min.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 49 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

Young (18-30), Healthy, Recreationally active, but untrained (not meeting ACSM's recommendations of 150 min/week of moderate-vigorous aerobic exercise) -

Exclusion Criteria:

Cardiovascular disease Smoking Subjects who were exercising regularly (\>75 min/week) were excluded.

\-
```

## Arms

- **4-s sprint inertial load training** (EXPERIMENTAL) — Participants trained three times a week for eight weeks following the training program consisting of 30 bouts of 4s all-out cycling on an inertial-load ergometer with progressively decreasing recovery time (30 to 24 to 15s).

## Interventions

- **4-s sprint inertial load training** (OTHER) — A program employing 30 bouts of 4s inertial load sprint training with progressively reduced recovery time (30 to 15 s) between sprints is effective for improving blood volume, VO2peak and maximal power.

## Primary Outcomes

- **Cardiovascular changes** _(time frame: Pre and post training (8 weeks))_ — Maximal oxygen consumption (VO2max) is an indicator of health and fitness. The investigators measured VO2max with a graded exercise using electronically braked cycling ergometer.
- **Blood volume changes** _(time frame: Pre and post training (8 weeks))_ — Hematological variables can effect the performance of the people. The investigators measured total blood volume, red blood cell volume, and plasma volume before and after training.

## Secondary Outcomes

- **Performance changes** _(time frame: Pre and post training (8 weeks))_

## Locations (1)

- Human Performance Laboratory, Department of Kinesiology and Health Education, the University of Texas at Austin, Austin, Texas, United States

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.human performance laboratory, department of kinesiology and health education, the university of texas at austin|austin|texas|united states` — added _(2026-05-12)_

---

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*Source data (authoritative): https://clinicaltrials.gov/study/NCT04656509*  
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