---
title: COVID-19 And Lingering Symptoms In Primary Care Patients
nct_id: NCT04813731
overall_status: COMPLETED
sponsor: Katarina Hedin
study_type: OBSERVATIONAL
primary_condition: Covid19
countries: Belgium, Denmark, France, Georgia, Germany, Ireland, Italy, Netherlands, Poland, Romania, Sweden
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04813731.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04813731"
ct_last_update_post_date: 2025-09-04
last_seen_at: "2026-05-12T06:24:44.485Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# COVID-19 And Lingering Symptoms In Primary Care Patients

**NCT ID:** [NCT04813731](https://clinicaltrials.gov/study/NCT04813731)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 300
- **Lead Sponsor:** Katarina Hedin
- **Collaborators:** Research Unit for General Practice in Aalborg, Utrecht University, National University of Ireland, Galway, Ireland, Region Jönköping County
- **Conditions:** Covid19, Symptoms and Signs
- **Start Date:** 2020-12-12
- **Completion Date:** 2022-06-30
- **CT.gov Last Update:** 2025-09-04

## Brief Summary

The ongoing corona virus disease 2019 (COVID-19) is a viral acute respiratory tract infection caused by server acute respiratory syndrom coronavirus typ 2 (SARS-CoV-2). The signs and symptom of SARS-CoV-2 infection vary and most people with COVID-19 experience illness of mild or moderate severity and recover with symptomatic treatment outside of hospital. Studies have found that some people experience lingering/long-lasting symptoms and only a minority of patients were completely free from COVID-19 related symptoms after two months. About one third still had up to two residual symptoms and 55% had three or more. As far as we know no study on lingering symptoms has been published in patients after a mild or moderate infection managed in primary care settings. The aim of this study is to explore the course of disease over a one year period and describe lingering symptoms and their impact on well-being and daily activities in adult non-hospitalized patients with previous established COVID-19 infection.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Confirmed SARS-CoV-2 infection, either by polymeras chain reaction (PCR), or by antigen testing (if authorized/recommended/used by national/local governments)
* Symptoms consistent with mild to moderate COVID-19
* Maximum of 2 weeks since positive SARS-CoV-2 test
* Aged 18 years and older
* Patient able and willing to comply with monthly phone calls.

Exclusion Criteria:

* Hospitalisation due to COVID-19
```

## Primary Outcomes

- **Time to full recovery symptoms** _(time frame: through study completion, a maximum of 1 year)_ — Number of weeks until "back to normal"

## Locations (13)

- Centre for General Practice, Department of Family Medicine & Population Health (FAMPOP), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
- the Academic Centre for General Practice (ACHG), Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium
- Center for General Practice at Aalborg University, Aalborg, Denmark
- Département de Santé Publique, Université Côte d'Azur, Centre Hospitalier Universitaire de Nice, Nice, France, Nice, France
- R. Lugar Center for Public Health Research, Tbilisi, Georgia
- Institut für Allgemeinmedizin Universitätsklinikum Würzburg Josef-Schneider-Str. 2/D7 97080 Würzburg, Würzburg, Germany
- School of Medicine, National University of Ireland, Galway, Ireland
- Covid-19 primary care special unit Sassuolo, Azienda Unità Sanitaria locale di Modena, Modena, Italy, Modena, Italy
- Julius Center, University Medical Center Utrecht, Utrecht, Netherlands
- Medical University of Lodz, Lodz, Lodz, Poland
- Balan Medfam SRL, Cluj-Napoca, Romania
- Wetterhälsan Primary Health Care Centre, Jönköping, Sweden
- Kärna Primary Health Care Centre, Linköping, Sweden

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.centre for general practice, department of family medicine & population health (fampop), faculty of medicine and health sciences, university of antwerp|antwerp||belgium` — added _(2026-05-12)_
- `locations.the academic centre for general practice (achg), department of public health and primary care, ku leuven|leuven||belgium` — added _(2026-05-12)_
- `locations.center for general practice at aalborg university|aalborg||denmark` — added _(2026-05-12)_
- `locations.département de santé publique, université côte d'azur, centre hospitalier universitaire de nice, nice, france|nice||france` — added _(2026-05-12)_
- `locations.r. lugar center for public health research|tbilisi||georgia` — added _(2026-05-12)_
- `locations.institut für allgemeinmedizin universitätsklinikum würzburg josef-schneider-str. 2/d7 97080 würzburg|würzburg||germany` — added _(2026-05-12)_
- `locations.school of medicine, national university of ireland|galway||ireland` — added _(2026-05-12)_
- `locations.covid-19 primary care special unit sassuolo, azienda unità sanitaria locale di modena, modena, italy|modena||italy` — added _(2026-05-12)_
- `locations.julius center, university medical center utrecht|utrecht||netherlands` — added _(2026-05-12)_
- `locations.medical university of lodz, lodz|lodz||poland` — added _(2026-05-12)_
- `locations.balan medfam srl|cluj-napoca||romania` — added _(2026-05-12)_
- `locations.wetterhälsan primary health care centre|jönköping||sweden` — added _(2026-05-12)_
- `locations.kärna primary health care centre|linköping||sweden` — added _(2026-05-12)_

---

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*Source data (authoritative): https://clinicaltrials.gov/study/NCT04813731*  
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