---
title: Pediatric Validation of CONOX Monitor During Surgery
nct_id: NCT04826146
overall_status: UNKNOWN
sponsor: Patricio Gonzalez Pizarro
study_type: OBSERVATIONAL
primary_condition: Anesthesia
countries: Spain
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04826146.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04826146"
ct_last_update_post_date: 2021-09-09
last_seen_at: "2026-05-12T06:14:50.685Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Pediatric Validation of CONOX Monitor During Surgery

**Official Title:** Monitoring the Depth of Anesthesia Using the qCON and qNOX Indices During Pediatric Surgery: a Multi-centre Study

**NCT ID:** [NCT04826146](https://clinicaltrials.gov/study/NCT04826146)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 65
- **Lead Sponsor:** Patricio Gonzalez Pizarro
- **Conditions:** Anesthesia, Anesthesia Awareness, Nociceptive Pain, Pediatric ALL, Surgery, Pain
- **Start Date:** 2020-07-01
- **Completion Date:** 2021-12-30
- **CT.gov Last Update:** 2021-09-09

## Brief Summary

Pediatric Validation of CONOX Monitoring device (qCON and qNOX indices) for anesthesia depth during surgery

## Eligibility

- **Minimum age:** 1 Year
- **Maximum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* General Anesthesia using propofol, sevoflurane or desflurane
* ASA I - IV
* Surgical procedure longer than 60 minutes

Exclusion Criteria:

* Neurological disorders
* Inability to correctly place BIS and CONOX probes in forehead
* Pregnancy
* Active prescription for drugs involving chronic pain and / or central nervous system
* Hemodynamic instability
```

## Arms

- **CONOX** — Patients are monitored with BIS and CONOX

## Interventions

- **Validation of qCON versus BIS** (DEVICE) — Correlation between qCON and BIS values (main outcome) and qNOX and MOAA/S scale are determined

## Primary Outcomes

- **Correlation of qCOX and BIS values** _(time frame: prospective data acquisition through study completion, an average of 1 year)_ — Both values are correlated by a blind investigator

## Secondary Outcomes

- **Correlation of qNOX and MOAA/S values** _(time frame: prospective data acquisition through study completion, an average of 1 year)_

## Locations (2)

- Hospital Universitario La Paz, Madrid, Spain
- Hospital Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain

## Recent Field Changes (last 30 days)

- `eligibility.sex` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.hospital universitario la paz|madrid||spain` — added _(2026-05-12)_
- `locations.hospital universitario de santiago de compostela (chus)|santiago de compostela||spain` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT04826146.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT04826146*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*