---
title: Impact of PD1-lymphocytes in Bronchoalveolar Lavage of Patients With Lung Cancer
nct_id: NCT04827667
overall_status: UNKNOWN
sponsor: University of Vienna
study_type: OBSERVATIONAL
primary_condition: Lung Cancer
countries: Austria
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04827667.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04827667"
ct_last_update_post_date: 2021-04-06
last_seen_at: "2026-05-12T07:19:13.785Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Impact of PD1-lymphocytes in Bronchoalveolar Lavage of Patients With Lung Cancer

**NCT ID:** [NCT04827667](https://clinicaltrials.gov/study/NCT04827667)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 40
- **Lead Sponsor:** University of Vienna
- **Conditions:** Lung Cancer
- **Start Date:** 2021-03-18
- **Completion Date:** 2021-12-31
- **CT.gov Last Update:** 2021-04-06

## Brief Summary

The aim of this trial is to assess PD1-lymphocytes in bronchoalveolar lavage in patients with lung cancer, ILD and asthma.

## Detailed Description

In this trial, 20 patients with lung cancer, 10 patients with asthma and 10 patients with interstitial lung disease who have to undergo bronchocospy for medical reasons are enrolled. In each patient, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* age \>18 years
* patients with lung cancer, asthma or ILD and indication for bronchoscopy for medical reasons
* Ability to provide informed consent

Exclusion Criteria:

* acute excacerbation in patients with asthma or ILD
* endoluminal tumor growth or penumonia in patients with lung cancer
```

## Arms

- **Patients with lung cancer** — In lung cancer patients with indication for bronchoscopy, bronchoalveolar lavage is performed to assess PD1-lymphocytes.
- **Patients wiht interstitial lung disease** — In patients with interstitial lung disease with indication for bronchoscopy, bronchoalveolar lavage is performed to assess PD1-lymphocytes.
- **Patients with asthma** — In patients with asthma with indication for bronchoscopy, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

## Interventions

- **bronchoalveolar lavage** (DIAGNOSTIC_TEST) — Bronchoalveolar lavage is performed by instillation and suction of saline in the middle lobe during bronchoscopy. Cytological examination and flow cytometry will be performed to assess PD-1lymphoctes.

## Primary Outcomes

- **To assess and compare PD1-lmyphocytes in bronchoalveolar lavage in patients with malignant and benign lung diseases to evluate their impact in lung cancer patients** _(time frame: 6 months)_

## Locations (1)

- Medical University of Vienna, Vienna, Austria — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.medical university of vienna|vienna||austria` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT04827667.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT04827667*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*