---
title: Important Data on COVID-19 Profile in Africa
nct_id: NCT04847817
overall_status: COMPLETED
sponsor: Centre de Recherche Médicale de Lambaréné
study_type: OBSERVATIONAL
primary_condition: Coronavirus Infection
countries: Gabon
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04847817.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04847817"
ct_last_update_post_date: 2022-07-19
last_seen_at: "2026-05-12T06:50:03.485Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Important Data on COVID-19 Profile in Africa

**NCT ID:** [NCT04847817](https://clinicaltrials.gov/study/NCT04847817)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 574
- **Lead Sponsor:** Centre de Recherche Médicale de Lambaréné
- **Collaborators:** European and Developing Countries Clinical Trials Partnership (EDCTP), Leiden University Medical Center, Institut de recherche en santé de surveillance épidémiologique et de formation, Université des Sciences de la Santé, Armauer Hansen Research Institute, Ethiopia, Universität Tübingen
- **Conditions:** Coronavirus Infection, Africa
- **Start Date:** 2020-08-01
- **Completion Date:** 2022-03-01
- **CT.gov Last Update:** 2022-07-19

## Brief Summary

The purpose of this study is to Understand the natural history of Coronavirus 2019 (COVID-19) infection to better define the period of infectiousness and transmissibility and to establish biobanks of COVID-19 blood and mucosal samples.

## Detailed Description

In this study ,the participants will be enrolled sequentially in the COVID-19 care referral centers. The infected hospitalized patient will be identified by the physicians in hospital. After the patient has given his/her informed consent the permission will be sought from him to approach his household contacts. The household contacts will be screened, and included in the study.

Patients hospitalized and positive for COVID-19 by PCR and their household contacts of all ages and gender (40% minimum of female), will be enrolled upon receipt of written informed consent.

## Eligibility

- **Sex:** ALL

```
Inclusion Criteria:

* Molecular (PCR) confirmed COVID-19 patients hospitalized in referral centers,
* Household contacts of hospitalized COVID-19 patient,
* Provided signed informed consent.

Exclusion Criteria:

* Pregnancy
```

## Arms

- **Index cases** — Patients infected by SARS-Cov2 Polymerase Chain Reaction (PCR) and hospitalized in a referral center for COVID-19 .
- **Households cases** — Household contacts of SARS-Cov2 hospitalized COVID-19 patients.

## Primary Outcomes

- **clinical and biological parameters of COVID-19** _(time frame: 14 days)_ — Infection and disease progression - Pattern of virus transmission
- **SARS-CoV-2 transmissibility** _(time frame: 14 days)_ — proportion of household contact who will become positive for SARS-COV2 using PCR

## Locations (2)

- Centre de Recherches Médicales de Lammbaréné, Lambaréné, Moyen-Ogooué Province, Gabon
- Centre de Recherches Médicales de Lambréné, Lambaréne, Gabon

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.centre de recherches médicales de lammbaréné|lambaréné|moyen-ogooué province|gabon` — added _(2026-05-12)_
- `locations.centre de recherches médicales de lambréné|lambaréne||gabon` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT04847817.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT04847817*  
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