---
title: The ECOVITA Study - Validation of LUS Score in SARS-CoV-2 Disease, i.e COVID-19
nct_id: NCT04871685
overall_status: UNKNOWN
sponsor: University of Campania Luigi Vanvitelli
study_type: OBSERVATIONAL
primary_condition: Respiratory Distress Syndrome
countries: Italy
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04871685.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04871685"
ct_last_update_post_date: 2021-05-04
last_seen_at: "2026-05-12T06:46:16.685Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# The ECOVITA Study - Validation of LUS Score in SARS-CoV-2 Disease, i.e COVID-19

**Official Title:** ECOVITA Study. Observational Study on Sars-COV 2 Population Hospitalized in the Italian Country

**NCT ID:** [NCT04871685](https://clinicaltrials.gov/study/NCT04871685)

## Key Facts

- **Status:** UNKNOWN
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 950
- **Lead Sponsor:** University of Campania Luigi Vanvitelli
- **Conditions:** Respiratory Distress Syndrome
- **Start Date:** 2020-10-18
- **Completion Date:** 2021-05-03
- **CT.gov Last Update:** 2021-05-04

## Brief Summary

Lung Ultrasound (LUS) has been revealing an extremely useful tool to identify and monitor complications from Sars-COV-2 disease. Recently, a research group has proposed a score, named LUS Score, able to optimize the use of this diagnostic technique. LUS Score is computed analyzing chest posterior and lateral spaces, considering the number of artefacts generated by the inflammed interstitium (B lines), the characteristics of the pleural line and the presence or not of consolidation areas.

The comparison between LUS and chest tomography (CT), the current gold standard for the diagnosis of interstitial pneumonia by COVID-19, has confirmed from the preliminary data, the reliability of such technique. Hence, the validation on a really large sample size of the ultrasound tool performed by dedicated personnel with high expertise, may allow the validation both in the clinical practice and in emergency and ordinary wards.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 90 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* men and women;
* confirmed COVID19 diagnosis after nasal-oropharyngeal swab;
* any symptom at hospitalization
* any therapy
* any pre-existing comorbidity

Exclusion Criteria:

* pregnant women
* healthy subjects with other respiratory diseases different from COVID-19
```

## Arms

- **Covid Center UOC Vanvitelli, Naples** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center Cotugno Hospital, Naples** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center "Del Mare Hospital", Naples** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center Santa Maria delle Grazie Hospital, Pozzuoli** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center Monaldi Hospital, Naples** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center Vannini Hospital, Rome** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center Bassini Hospital, ASST Milano Nord** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center Melfi Hospital** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units
- **Covid Center Messina University Hospital** — Patients hospitalized due to Sars-Cov-2 disease either in emergency or ordinary medicine/intensive care units

## Interventions

- **lung ultrasound** (DIAGNOSTIC_TEST) — the patients underwent to a non invasive diagnostic exam to identify and monitor clinical conditions and onset of respiratory complications due to COVID-19

## Primary Outcomes

- **validation of lung ultrasound score** _(time frame: 6 months)_ — validation of lung ultrasound in the clinical practice of diagnosis of complications of low respiratory tracts during COVID-19

## Secondary Outcomes

- **Association of LUS score with clinical outcome** _(time frame: 6 months)_
- **Association of LUS score with duration of hospitalization (days)** _(time frame: 6 months)_
- **Association of LUS score with respiratory support required** _(time frame: 6 months)_

## Locations (1)

- University of Campania Luigi Vanvitelli, Naples, Campania, Italy

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.university of campania luigi vanvitelli|naples|campania|italy` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT04871685.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT04871685*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*