---
title: Meal Timings, Appetite, Mood and Weight Loss in Individuals on a Commercial Intermittent Fasting Programme
nct_id: NCT04893772
overall_status: COMPLETED
sponsor: "King's College London"
study_type: OBSERVATIONAL
primary_condition: Weight Loss
countries: United Kingdom
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT04893772.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04893772"
ct_last_update_post_date: 2023-04-19
last_seen_at: "2026-05-12T07:12:52.815Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Meal Timings, Appetite, Mood and Weight Loss in Individuals on a Commercial Intermittent Fasting Programme

**Official Title:** Observational Study to Assess Associations Between Daily Meal Timings, Appetite, Mood and Weight Loss in Individuals Completing a Commercial Intermittent Fasting Programme

**NCT ID:** [NCT04893772](https://clinicaltrials.gov/study/NCT04893772)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 33
- **Lead Sponsor:** King's College London
- **Collaborators:** LighterLife (UK) Ltd
- **Conditions:** Weight Loss
- **Start Date:** 2021-06-30
- **Completion Date:** 2021-12-31
- **CT.gov Last Update:** 2023-04-19

## Brief Summary

Although individuals following commercial intermittent fasting programmes consume meal replacement products during fasting days, further behavioural variables such as time of food consumption, sleep quality and duration, appetite and mood may significantly impact weight loss and intervention success. This project aims to assess behavioural patterns (dietary intake, sleep, meal timing, physical activity), mood and appetite on both fasting and non-fasting days and to investigate whether these are associated with weight loss.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Those responding to adverts on the LighterLife Fast Challenge social media channels will be asked if they would like to participate

Exclusion Criteria:

* Those without access to a smart phone or laptop will not be eligible to take part in the study due to the need to report variables daily
```

## Interventions

- **Intermittent fasting** (DIETARY_SUPPLEMENT) — Three "fasting" days a week, whereby participants consume 600-800 kcal/day from 4 meal replacement products: breakfast, lunch, a snack and dinner. During the other 4 non-fasting "smart" days each week, participants are instructed to consume 2 x 300 kcal meals and 2 x 100 kcal snacks, from a selection of recipes, plus one meal of their own choosing.

## Primary Outcomes

- **Body weight in kg** _(time frame: Change in body weight up to 12 weeks)_ — Weighed at home

## Secondary Outcomes

- **Sleep duration** _(time frame: Before weight loss programme (day 0))_
- **Sleep quality** _(time frame: Before weight loss programme (day 0))_
- **Physical activity** _(time frame: Before weight loss programme (day 0))_
- **Meal timings** _(time frame: Before weight loss programme (day 0))_
- **How hungry do you feel?** _(time frame: Daily from day 1 up to 12 weeks)_
- **How satisfied do you feel?** _(time frame: Daily from day 1 up to 12 weeks)_
- **How full do you feel?** _(time frame: Daily from day 1 up to 12 weeks)_
- **How much do you think you can eat?** _(time frame: Daily from day 1 up to 12 weeks)_
- **Would you like to eat something sweet?** _(time frame: Daily from day 1 up to 12 weeks)_
- **Would you like to eat something salty?** _(time frame: Daily from day 1 up to 12 weeks)_
- **Would you like to eat something savoury?** _(time frame: Daily from day 1 up to 12 weeks)_
- **Would you like to eat something fatty?** _(time frame: Daily from day 1 up to 12 weeks)_
- **Overall my mood is (very unpleasant to very pleasant)** _(time frame: Daily from day 1 up to 12 weeks)_
- **Mindfulness - I was finding to difficult to stay focused on what I was doing** _(time frame: Weekly from week 1 up to 12 weeks)_
- **Mindfulness - I was doing something without paying attention** _(time frame: Weekly from week 1 up to 12 weeks)_
- **Mindfulness - I was preoccupied with the future or the past** _(time frame: Weekly from week 1 up to 12 weeks)_
- **Mindfulness - I was doing something automatically without being aware of what I was doing** _(time frame: Weekly from week 1 up to 12 weeks)_
- **Mindfulness - I was rushing through something without really being attentive to it.** _(time frame: Weekly from week 1 up to 12 weeks)_
- **Height** _(time frame: Before weight loss programme (day 0))_
- **Dietary intake (macronutrients and energy)** _(time frame: Before weight loss programme (day 0))_
- **Diet quality** _(time frame: Before weight loss programme (day 0))_
- **Dietary intake (macronutrients and energy)** _(time frame: Non-fasting days: Weeks 1, 2, 3, 4, 8 and 12)_
- **Diet quality** _(time frame: Non-fasting days: Weeks 1, 2, 3, 4, 8 and 12)_
- **Meal replacement product choice** _(time frame: Fasting days: Weeks 1, 2, 3, 4, 8 and 12)_
- **Meal replacement product timings** _(time frame: Fasting days: Weeks 1, 2, 3, 4, 8 and 12)_
- **Sleep duration** _(time frame: Daily from day 1 up to 12 weeks)_
- **Sleep quality** _(time frame: Daily from day 1 up to 12 weeks)_
- **Physical activity** _(time frame: Daily from day 1 up to 12 weeks)_
- **Alcohol use** _(time frame: Before weight loss programme (day 0))_

## Locations (1)

- Department of Nutritional Sciences, King's College London, London, United Kingdom

## Recent Field Changes (last 30 days)

- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.department of nutritional sciences, king's college london|london||united kingdom` — added _(2026-05-12)_

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*Canonical: https://parkinsonspathways.com/agent/trials/NCT04893772.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT04893772*  
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