--- title: Nutritional Study on the Beneficial Effects of Canned Fish Consumption on Healthy Adult Population nct_id: NCT05213273 overall_status: COMPLETED phase: NA sponsor: Sara Arranz Martinez study_type: INTERVENTIONAL primary_condition: Healthy Diet countries: Spain canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05213273.md" clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05213273" ct_last_update_post_date: 2023-12-01 last_seen_at: "2026-05-12T06:19:21.885Z" source: ClinicalTrials.gov (mirrored, no enrichment) --- # Nutritional Study on the Beneficial Effects of Canned Fish Consumption on Healthy Adult Population **Official Title:** TUNACAN: Nutritional Study on the Beneficial Effects of Canned Fish Consumption on Healthy Adult Population **NCT ID:** [NCT05213273](https://clinicaltrials.gov/study/NCT05213273) ## Key Facts - **Status:** COMPLETED - **Phase:** NA - **Study Type:** INTERVENTIONAL - **Target Enrollment:** 152 - **Lead Sponsor:** Sara Arranz Martinez - **Collaborators:** MUTUALIA S.L., OSARTEN KOOPERATIBA ELKARTEA - **Conditions:** Healthy Diet - **Start Date:** 2021-11-01 - **Completion Date:** 2022-07-30 - **CT.gov Last Update:** 2023-12-01 ## Brief Summary There is sufficient evidence on the beneficial effects of fish consumption on health, mainly associated with the content of omega-3 polyunsaturated fatty acids (EPA and DHA) present mainly in blue fish. Different national and international organizations have issued recommendations on the optimal amount of fish that the population should consume to prevent certain chronic diseases related to diet. Thus, the WHO recommends eating fish regularly (1-2 servings per week for healthy adults) to ideally provide the equivalent of 250 mg of omega-3 fatty acids (EPA + DHA). Not reaching the optimal levels of EPA + DHA increases the risk for cardiovascular diseases, increasing the risk of death according to certain epidemiological studies. In this sense, using more precise techniques such as membrane lipidomics, allow adequate quantification and monitoring of fatty acid levels present in our body and how this lipid profile can change according to metabolism and diet. The objective of this study is to carry out a clinical trial of nutritional intervention with an adult population without pathologies that has a low consumption of fish (\<2 servings / week) to evaluate the effectiveness of an intervention strategy based on increasing the number of fish servings through a controlled intake of fresh and canned fish. The results aim to show that increasing fish intake has an impact on lipid metabolism and in the future, for the prevention of certain chronic diseases, the introduction of canned fish can be a healthy strategy to increase fish consumption to long term. ## Detailed Description Objectives: The main objective of this study is to demonstrate through a nutritional intervention, the benefits of the intake of canned fish compared to fresh or frozen fish on lipid metabolism in a healthy adult population, which can be divided into three specific objectives: * Assessment of the health benefits of consuming canned fish (controlled intake): impact on the fatty acid profile of red blood cell membrane. * Provide evidence of the benefits of consuming canned fish compared to intake fresh / frozen fish. * Demystify the bad reputation of canned fish products (as processed foods). Study design: A prospective, randomized, controlled, parallel-group nutritional intervention clinical trial will be carried out with 150 healthy adults between 18 and 65 years for 4 months. Participants will be randomized into one of the two equal size intervention groups: "group A: fresh/frozed fish" or "group B: canned fish". Recruitment and selection of participants: AZTI will organize the selection and recruitment process in collaboration with IMQ-Prevention (MUTUALIA) through 4 centers in Spain (Zamudio, Bilbao, Vitoria and Donosti) and with the OSARTEN Koop clinical analysis laboratory. Participants will be distributed according to a random assignment sequence. In this way, investigators increase the probability that the two groups (control and intervention) are comparable with respect to age and gender. Inclusion criteria: Healthy adults (men and women) with 18.5 \