---
title: "Er:YAG Laser Treatment of Moderate Chronic Periodontitis"
nct_id: NCT05217823
overall_status: COMPLETED
phase: NA
sponsor: Plovdiv Medical University
study_type: INTERVENTIONAL
primary_condition: Chronic Periodontitis, Generalized, Moderate
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05217823.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05217823"
ct_last_update_post_date: 2022-02-23
last_seen_at: "2026-05-12T06:57:33.785Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Er:YAG Laser Treatment of Moderate Chronic Periodontitis

**Official Title:** Long-term Stability of Er:YAG Laser Non-surgical Periodontal Treatment

**NCT ID:** [NCT05217823](https://clinicaltrials.gov/study/NCT05217823)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 30
- **Lead Sponsor:** Plovdiv Medical University
- **Conditions:** Chronic Periodontitis, Generalized, Moderate
- **Start Date:** 2012-01
- **Completion Date:** 2014-02
- **CT.gov Last Update:** 2022-02-23

## Brief Summary

The Er:YAG laser possesses specific characteristics allowing to be used in non-surgical periodontal treatment. The aim of the resent study was to evaluate the long-term clinical effectiveness of Er:YAG laser monotherapy in the treatment of moderate chronic periodontitis and to compare it with conventional hand instrumentation.

MATERIALS AND METHODS: 451 teeth (1,099 periodontal pockets) from 30 patients with moderate chronic periodontitis (initial probing pocket depth 4 to 6 mm) were allocated for subgingival scaling and root planing in two groups - hand instrumentation (control) and Er:YAG laser instrumentation with 100mJ/15Hz (test). Using a computerized periodontal probe, patients were examined for probing pocket depth (PPD), gingival recession (GR), clinical attachment level (CAL), bleeding on probing (BOP), plaque presence (FMPS) at baseline, one, three, six and 12 months after instrumentation.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* at least two teeth per quadrant with PPD between 3,6 mm and 6,4 mm;
* loss of clinical attachment up to 4 mm
* bleeding on probing

Exclusion Criteria:

* periodontal treatment in the last 12 months;
* systemic diseases;
* systemic medication
```

## Arms

- **Er:YAG laser** (EXPERIMENTAL) — Teeth treated with Er:YAG laser
- **Hand instruments** (ACTIVE_COMPARATOR) — Teeth treated with Gracey curettes

## Interventions

- **Er:YAG laser** (DEVICE)
- **hand instruments** (OTHER)

## Primary Outcomes

- **Probing pocket depth** _(time frame: 1 year)_ — Change in PPD (measured as a distance between the gingival margin and the depth of the pocket) using computerised periodontal probe

## Secondary Outcomes

- **Gingival recession** _(time frame: 1 year)_
- **Clinical attachment level** _(time frame: 1 year)_
- **Bleeding on probing** _(time frame: 1 year)_
- **Plaque level** _(time frame: 1 year)_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT05217823.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT05217823*  
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