---
title: Glioblastoma and Individualized Therapies
nct_id: NCT05356312
overall_status: AVAILABLE
sponsor: Zentrum fur Humangenetik Tuebingen
study_type: EXPANDED_ACCESS
primary_condition: Glioma, Malignant
countries: Germany
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05356312.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05356312"
ct_last_update_post_date: 2024-03-01
last_seen_at: "2026-05-12T06:29:33.885Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Glioblastoma and Individualized Therapies

**Official Title:** Retrospective Analysis of Glioblastoma Patients With Immune Therapies

**NCT ID:** [NCT05356312](https://clinicaltrials.gov/study/NCT05356312)

## Key Facts

- **Status:** AVAILABLE
- **Study Type:** EXPANDED_ACCESS
- **Lead Sponsor:** Zentrum fur Humangenetik Tuebingen
- **Conditions:** Glioma, Malignant
- **CT.gov Last Update:** 2024-03-01

## Brief Summary

The treatment of patients with World Health Organization (WHO) grade 4 malignant glioma has not seen any significant breakthrough the past years. Following surgery and radio / chemotherapy patients still experience a very high recurrence risk and the prognosis is dismal. The investigators observed patients with grade IV malignant glioma receiving individualized treatment based on their molecular profile including fully personalized vaccines.

## Eligibility

- **Sex:** ALL

```
Inclusion Criteria:

* malignant glioma, IDH WT

Exclusion Criteria:

* na
```

## Interventions

- **Vaccination** (BIOLOGICAL) — Personalized neoantigen vaccination

## Locations (1)

- Zentrum für Humangenetik Tübingen, Tübingen, Germany — _AVAILABLE_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.zentrum für humangenetik tübingen|tübingen||germany` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT05356312.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT05356312*  
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