--- title: Cataract Surgery Technique and Ocular Clarity nct_id: NCT05489198 overall_status: UNKNOWN phase: NA sponsor: Amphia Hospital study_type: INTERVENTIONAL primary_condition: Cataract canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05489198.md" clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05489198" ct_last_update_post_date: 2022-08-05 last_seen_at: "2026-05-12T06:37:30.913Z" source: ClinicalTrials.gov (mirrored, no enrichment) --- # Cataract Surgery Technique and Ocular Clarity **Official Title:** Ocular Clarity After Cataract Surgery With Two Different Phacoemulsification Systems **NCT ID:** [NCT05489198](https://clinicaltrials.gov/study/NCT05489198) ## Key Facts - **Status:** UNKNOWN - **Phase:** NA - **Study Type:** INTERVENTIONAL - **Target Enrollment:** 15 - **Lead Sponsor:** Amphia Hospital - **Conditions:** Cataract - **Start Date:** 2022-09 - **Completion Date:** 2023-09 - **CT.gov Last Update:** 2022-08-05 ## Brief Summary The goal of this study is to study the restoration of quality of vision, expressed as straylight, in the immediate period after cataract surgery with two different phacoemulsification technologies. ## Detailed Description Cataract is an opacification of the lens. With cataract surgery, the lens is surgically removed after which a clear artificial intraocular lens is implanted. For patients, it is important that they regain functional vision as quickly as possible after surgery as a limited vision may increase the risk of falling and increases the dependency on other people. Surgical removal of the lens is done with a phacoemulsification system. Differences between phacoemulsification systems are the used pump type, the way the needle oscillates, and the fluid dynamics of the system. It is unknown whether any of the available systems offer an advantage on the amount of corneal oedema that develops after surgery and, therefore, results in a more rapid restoration of functional vision. ## Eligibility - **Minimum age:** 18 Years - **Sex:** ALL - **Healthy Volunteers:** No ``` Inclusion Criteria: * Diagnosis of cataract in both eyes, * Having consented to and is planned to undergo cataract surgery in both eyes, * Planned for implantation of a non-toric monofocal intraocular lens (IOL) in both eyes, * A targeted refractive error of emmetropia, * Corneal astigmatism of ≤1.5 D, * Age of at least 18 years, * Willing and able to participate in both preoperative and postoperative examinations, and * Agreeing to sign the informed consent form. Exclusion Criteria: * Insufficient understanding of the Dutch language to comply with study procedures, * Any comorbidity (other than cataract) that may significantly affect visual function and/or increase straylight and/or prolong visual recovery after surgery, such as significant macular degeneration, significant glaucoma, significant diabetic eye disease, significant ocular surface disease, cornea dystrophy, corneal opacification, significant vitreous opacities (such as asteroid hyalosis and clinically significant floaters), and history of cerebral vascular accident, * Subjects with a history of ocular surgery (e.g., corneal refractive surgery), * Subjects with an increased risk of complicated cataract surgery: * Lens subluxation or (phaco)iridodonesis, * Cataract brunescens, cataract rubra, cataract nigrans, or posterior polar cataract, and * History of ocular trauma, * Unability to be (reliably) measured with the C-Quant straylight meter or Pentacam corneal topographer, and * A calculated IOL power in any eye that prohibits implantation of the same type of IOL in both eyes. ``` ## Arms - **Centurion** (EXPERIMENTAL) — Cataract surgery performed with the Centurion phacoemulsification system - **Quatera 700** (EXPERIMENTAL) — Cataract surgery performed with the Quatera 700 phacoemulsification system ## Interventions - **cataract surgery with Centurion phacoemulsification system** (PROCEDURE) — Cataract surgery performed with the Centurion phacoemulsification system - **cataract surgery with Quatera 700 phacoemulsification system** (PROCEDURE) — Cataract surgery performed with the Quatera 700 phacoemulsification system ## Primary Outcomes - **Straylight** _(time frame: preoperative)_ — Amount of straylight measured with C-Quant, expressed as log(s) - **Straylight** _(time frame: 1-2 hours after surgery)_ — Amount of straylight measured with C-Quant, expressed as log(s) - **Straylight** _(time frame: 1 day after surgery)_ — Amount of straylight measured with C-Quant, expressed as log(s) - **Straylight** _(time frame: 1 week after surgery)_ — Amount of straylight measured with C-Quant, expressed as log(s) - **Straylight** _(time frame: 1 month after surgery)_ — Amount of straylight measured with C-Quant, expressed as log(s) ## Secondary Outcomes - **Corneal densitometry** _(time frame: preoperative)_ - **Corneal densitometry** _(time frame: 1-2 hours after surgery)_ - **Corneal densitometry** _(time frame: 1 day after surgery)_ - **Corneal densitometry** _(time frame: 1 week after surgery)_ - **Corneal densitometry** _(time frame: 1 month after surgery)_ - **Amount of phaco energy used** _(time frame: Surgery day)_ - **Amount of balanced salt solution used** _(time frame: Surgery day)_ - **Total surgery time** _(time frame: Surgery day)_ - **Uncorrected Distance Visual Acuity** _(time frame: preoperative)_ - **Uncorrected Distance Visual Acuity** _(time frame: 1-2 hours after surgery)_ - **Uncorrected Distance Visual Acuity** _(time frame: 1 day after surgery)_ - **Uncorrected Distance Visual Acuity** _(time frame: 1 week after surgery)_ - **Uncorrected Distance Visual Acuity** _(time frame: 1 month after surgery)_ - **Corrected Distance Visual Acuity** _(time frame: preoperative)_ - **Corrected Distance Visual Acuity** _(time frame: 1 day after surgery)_ - **Corrected Distance Visual Acuity** _(time frame: 1 week after surgery)_ - **Corneal pachymetry** _(time frame: 1 month after surgery)_ - **Corneal pachymetry** _(time frame: preoperative)_ - **Corneal pachymetry** _(time frame: 1-2 hours after surgery)_ - **Corneal pachymetry** _(time frame: 1 day after surgery)_ - **Corneal pachymetry** _(time frame: 1 week after surgery)_ - **Presence of corneal oedema** _(time frame: preoperative)_ - **Presence of corneal oedema** _(time frame: 1-2 hours after surgery)_ - **Presence of corneal oedema** _(time frame: 1 day after surgery)_ - **Presence of corneal oedema** _(time frame: 1 week after surgery)_ - **Presence of corneal oedema** _(time frame: 1 month after surgery)_ - **Catquest-9SF** _(time frame: preoperative)_ - **Catquest-9SF** _(time frame: 1-2 hours after surgery)_ - **Catquest-9SF** _(time frame: 1 day after surgery)_ - **Catquest-9SF** _(time frame: 1 week after surgery)_ - **Catquest-9SF** _(time frame: 1 month after surgery)_ - **Patient-Perceived Satisfactory Improvement in Vision** _(time frame: 1-2 hours after surgery)_ - **Patient-Perceived Satisfactory Improvement in Vision** _(time frame: 1 day after surgery)_ - **Patient-Perceived Satisfactory Improvement in Vision** _(time frame: 1 week after surgery)_ - **Patient-Perceived Satisfactory Improvement in Vision** _(time frame: 1 month after surgery)_ ## Recent Field Changes (last 30 days) - `status.overallStatus` — added _(2026-05-12)_ - `status.primaryCompletionDate` — added _(2026-05-12)_ - `status.completionDate` — added _(2026-05-12)_ - `status.lastUpdatePostDate` — added _(2026-05-12)_ - `design.phases` — added _(2026-05-12)_ - `design.enrollmentCount` — added _(2026-05-12)_ - `eligibility.criteria` — added _(2026-05-12)_ - `eligibility.minAge` — added _(2026-05-12)_ - `eligibility.sex` — added _(2026-05-12)_ - `outcomes.primary` — added _(2026-05-12)_ - `outcomes.secondary` — added _(2026-05-12)_ - `armsInterventions.arms` — added _(2026-05-12)_ - `armsInterventions.interventions` — added _(2026-05-12)_ - `sponsor.lead` — added _(2026-05-12)_ - `results.hasResults` — added _(2026-05-12)_ --- *Canonical: https://parkinsonspathways.com/agent/trials/NCT05489198.md* *Source data (authoritative): https://clinicaltrials.gov/study/NCT05489198* *This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*