---
title: Enhancing Smoking Cessation Via Telehealth Options in Primary Care
nct_id: NCT05493254
overall_status: RECRUITING
phase: NA
sponsor: Medical University of South Carolina
study_type: INTERVENTIONAL
primary_condition: Smoking Cessation
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05493254.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05493254"
ct_last_update_post_date: 2026-03-05
last_seen_at: "2026-05-12T07:07:00.285Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Enhancing Smoking Cessation Via Telehealth Options in Primary Care

**Official Title:** Hybrid Type 1 Effectiveness-Implementation Trial of a Proactive Smoking Cessation Electronic Visit for Scalable Delivery Via Primary Care

**NCT ID:** [NCT05493254](https://clinicaltrials.gov/study/NCT05493254)

## Key Facts

- **Status:** RECRUITING
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 672
- **Lead Sponsor:** Medical University of South Carolina
- **Collaborators:** National Cancer Institute (NCI)
- **Conditions:** Smoking Cessation
- **Start Date:** 2022-08-31
- **Completion Date:** 2026-12-31
- **CT.gov Last Update:** 2026-03-05

## Brief Summary

The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation. Participants will be randomly assigned to receive either the smoking cessation e-visit or not. The e-visit will look similar to an online questionnaire asking about smoking history, motivation to quit, and preferences for medications for quitting smoking. Participants may receive a prescription for a smoking cessation medication as an outcome of the e-visit, if randomized to the e-visit group, but there is no requirement to take any medication. This study consists of questionnaires and breath samples provided at 4 separate time points throughout the study. Participation in this study will take about 24 weeks.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

1. current smoking, defined as 1+ cigarettes/day, for 20+ days out of the last 30 for the last 6+ months
2. age 18+
3. enrolled in MyChart or willing to enroll
4. possess a valid e-mail address that is checked daily
5. owner of an iOS or Android smartphone to provide remote CO
6. have a valid mailing address
7. English fluency

Exclusion Criteria:

1\) Use of an FDA-approved cessation medication in the last 7 days
```

## Arms

- **Smoking cessation electronic visit (e-visit)** (EXPERIMENTAL) — This group will be sent 1) an invitation to complete an electronic visit (e-visit) focused on cigarette smoking and 2) an invitation to complete a follow-up e-visit one-month after the initial e-visit.
- **Treatment as usual (TAU)** (ACTIVE_COMPARATOR) — This group will be provided information about the state quitline and about the importance of quitting smoking and it will be recommended that they contact their PCP to schedule a medical visit to discuss quitting smoking.

## Interventions

- **Smoking cessation e-visit** (BEHAVIORAL) — electronic visits (e-visits) for smoking cessation
- **Treatment As Usual** (BEHAVIORAL) — Information about the state quitline and about the importance of quitting smoking and a recommendation to contact one's PCP to schedule a medical visit to discuss quitting smoking.

## Primary Outcomes

- **Number of participants who utilized smoking cessation treatment** _(time frame: Month 1)_ — Number of participants who utilized smoking cessation treatment since last assessment.
- **Number of participants who utilized smoking cessation treatment** _(time frame: Month 3)_ — Number of participants who utilized smoking cessation treatment since last assessment.
- **Number of participants who utilized smoking cessation treatment** _(time frame: Month 6)_ — Number of participants who utilized smoking cessation treatment since last assessment.
- **Cigarettes smoking** _(time frame: Month 1)_ — Cigarettes per day reduction greater than 50%
- **Cigarettes smoking** _(time frame: Month 3)_ — Cigarettes per day reduction greater than 50%
- **Cigarettes smoking** _(time frame: Month 6)_ — Cigarettes per day reduction greater than 50%
- **Quit attempts** _(time frame: Month 1)_ — Quit attempts since last contact
- **Quit attempts** _(time frame: Month 3)_ — Quit attempts since last contact
- **Quit attempts** _(time frame: Month 6)_ — Quit attempts since last contact
- **Seven-day point prevalence abstinence** _(time frame: Month 1)_ — Participant has not had a cigarette in the past 7 days
- **Seven-day point prevalence abstinence** _(time frame: Month 3)_ — Participant has not had a cigarette in the past 7 days
- **Seven-day point prevalence abstinence** _(time frame: Month 6)_ — Participant has not had a cigarette in the past 7 days
- **E-visit Acceptability** _(time frame: Month 1)_ — The e-visit will be considered acceptable if the average score on the Acceptability of Intervention Measure (AIM) is greater than or equal to 4.
- **E-visit Acceptability** _(time frame: Month 3)_ — The e-visit will be considered acceptable if the average score on the Acceptability of Intervention Measure (AIM) is greater than or equal to 4.
- **E-visit Acceptability** _(time frame: Month 6)_ — The e-visit will be considered acceptable if the average score on the Acceptability of Intervention Measure (AIM) is greater than or equal to 4.
- **E-visit Adoption** _(time frame: Month 1)_ — Patients prescribed a medication who obtain their medication
- **E-visit Adoption** _(time frame: Month 3)_ — Patients prescribed a medication who obtain their medication
- **E-visit Adoption** _(time frame: Month 6)_ — Patients prescribed a medication who obtain their medication

## Locations (1)

- Medical University of South Carolina, Charleston, South Carolina, United States — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.medical university of south carolina|charleston|south carolina|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT05493254.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT05493254*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*