---
title: Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone.
nct_id: NCT05534334
overall_status: UNKNOWN
phase: PHASE2, PHASE3
sponsor: Beni-Suef University
study_type: INTERVENTIONAL
primary_condition: Oral Pyogenic Granuloma
countries: Egypt
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05534334.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05534334"
ct_last_update_post_date: 2022-09-14
last_seen_at: "2026-05-12T06:35:40.585Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone.

**Official Title:** Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone

**NCT ID:** [NCT05534334](https://clinicaltrials.gov/study/NCT05534334)

## Key Facts

- **Status:** UNKNOWN
- **Phase:** PHASE2, PHASE3
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 30
- **Lead Sponsor:** Beni-Suef University
- **Conditions:** Oral Pyogenic Granuloma
- **Start Date:** 2022-05-01
- **Completion Date:** 2022-11-29
- **CT.gov Last Update:** 2022-09-14

## Brief Summary

Gingival Pyogenic granuloma in the esthetic zone represents an esthetic problem. While surgical treatment may not give the premium esthetic demands, corticosteroid may acheive this balance.

## Detailed Description

In our practice, the investigators have found the use of topical steroids effectively induced regression of PGs. This protocol has been suggested by published case reports supported by the anti-inflammatory actions corticosteroid.

This is a particularly valuable approach for patients who have PG in the esthetic zone allowing the surgeon to keep maximum amount of periodontal tissues.

## Eligibility

- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Patients with oral pyogenic granuloma at the esthetic zone

Exclusion Criteria:

* Patients who were not compliant to oral hygiene instructions and can not be motivated
```

## Arms

- **Control arm** (ACTIVE_COMPARATOR) — Surgical excision of the gingival pyogenic granuloma
- **Intervention** (EXPERIMENTAL) — Intralesional injection with corticosteroids solution (1.8 mL of 100 mg hydrocortisone)

## Interventions

- **Solu-Cortef** (DRUG) — A vial sol. used for intra-mascular injection

## Primary Outcomes

- **Remaining width of the attached gingiva** _(time frame: 6 month)_ — Remaining width of the attached gingival it is measured using graduated probe

## Secondary Outcomes

- **Recurrence of the lesion** _(time frame: 6 months)_

## Locations (2)

- Beni_Suef University, Banī Suwayf, Beni Suweif Governorate, Egypt — _RECRUITING_
- Eman Ahmed, Banī Suwayf, Benisuef, Egypt — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.beni_suef university|banī suwayf|beni suweif governorate|egypt` — added _(2026-05-12)_
- `locations.eman ahmed|banī suwayf|benisuef|egypt` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT05534334.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT05534334*  
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