---
title: Effect of Music Therapy on the Anxiety Level of Patients During the Administration of Ocular Intravitreal Injections
nct_id: NCT05904392
overall_status: COMPLETED
phase: NA
sponsor: Althaia Xarxa Assistencial Universitària de Manresa
study_type: INTERVENTIONAL
primary_condition: Anxiety and Fear
countries: Spain
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05904392.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05904392"
ct_last_update_post_date: 2024-03-05
last_seen_at: "2026-05-12T07:20:10.313Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Effect of Music Therapy on the Anxiety Level of Patients During the Administration of Ocular Intravitreal Injections

**NCT ID:** [NCT05904392](https://clinicaltrials.gov/study/NCT05904392)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 50
- **Lead Sponsor:** Althaia Xarxa Assistencial Universitària de Manresa
- **Collaborators:** University of Vic - Central University of Catalonia
- **Conditions:** Anxiety and Fear
- **Start Date:** 2023-12-01
- **Completion Date:** 2024-02-28
- **CT.gov Last Update:** 2024-03-05

## Brief Summary

Introduction Ocular intravitreal injection is a widely used ophthalmic invasive technique to administer medication directly inside the patient's eye. Despite being usually a quick and painless intervention, some patients report nervousness and anxiety before and during the procedure. Music therapy could help in assessing this discomfort, as previous studies have shown it can beneficial, specially helping to reduce anxiety levels.

Objective This study aims to assess the effect of music therapy on patients undergoing intravitreal injections and how it affects their anxiety.

Methods This is a randomized, prospective, single blind, clinical trial. Patients will be divided into two groups. Group A patients will listen to classical music during the procedure (intervention). Group B patients (control), will not listen to music during the procedure. All other aspects of the procedure will be the same for both groups. To analyze the impact music therapy, patients will fill in the STAI anxiety questionnaire and will be evaluated with the pain visual analogue scale (VAS) before and after the injection procedure.

Expected results Subjects that undergo the procedure with music therapy are expected to experience less anxiety that the ones that do not. Less pain perception is also expected.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Patients must be at least 18 years old.
* Patients must have been prescribed an intravitreal injections of an anti-VEGF drug.
* Subjects must have undergone at least one previous intravitreal injection.
* Patients must fully understand the procedure and the project they will be participating in and agree on signing the informed consent.

Exclusion Criteria:

* Patients with a psychiatric diagnosis with the need to take anxiety medication.
* Patients that before the intervention took medication to relax, such as benzodiazepines or anxiolytics.
* Subjects with hearing difficulty.
```

## Arms

- **Intervention** (EXPERIMENTAL) — Music played prior to intravitreal injection
- **Control** (NO_INTERVENTION) — No music played.

## Interventions

- **Music** (OTHER) — Music played prior to injection

## Primary Outcomes

- **STAI** _(time frame: Just before and immediately after intervention)_ — Change in anxiety score test

## Locations (1)

- Eduard Pedemonte Sarrias, Manresa, Barcelona, Spain

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.eduard pedemonte sarrias|manresa|barcelona|spain` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT05904392.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT05904392*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*