---
title: Perioperative Vaping Complications
nct_id: NCT05912023
overall_status: ACTIVE_NOT_RECRUITING
sponsor: Navy Medical Center San Diego
study_type: OBSERVATIONAL
primary_condition: Vaping
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT05912023.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05912023"
ct_last_update_post_date: 2024-05-17
last_seen_at: "2026-05-12T06:57:25.214Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Perioperative Vaping Complications

**Official Title:** Vaping Associated Perioperative Pulmonary Complications - Anesthetic Implications

**NCT ID:** [NCT05912023](https://clinicaltrials.gov/study/NCT05912023)

## Key Facts

- **Status:** ACTIVE_NOT_RECRUITING
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 300
- **Lead Sponsor:** Navy Medical Center San Diego
- **Conditions:** Vaping, Complication of Anesthesia
- **Start Date:** 2023-07-28
- **Completion Date:** 2025-07-01
- **CT.gov Last Update:** 2024-05-17

## Brief Summary

Prospective observational study evaluating the incidence, and qualifying the types, of perioperative pulmonary complications in patients that vape.

## Detailed Description

The primary objective of our study is to determine the rate at which patients that vape or use e-cigarettes experience perioperative pulmonary complications during and following general anesthesia. Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated.

A secondary objective will be to further investigate and include the relationship between vaping cessation timeline in the preoperative period and the occurrence of PPCs, which is similarly underreported in the literature. Furthermore, the study will assess how effectively anesthesia providers are screening for vaping or e-cigarette use as part of the preoperative evaluation, given that "it is unclear whether anesthesiologists and surgeons routinely ask patients explicitly about vaping" in the pre-operative setting. This lack of representative screening for vaping further obscures an understanding of the relationship between vaping, vaping cessation, and PPCs.

## Eligibility

- **Minimum age:** 12 Years
- **Maximum age:** 80 Years
- **Sex:** ALL

```
Inclusion Criteria:

* Surgical Patient
* General Anesthesia
* Hx of vaping
* Age ≥12

Exclusion Criteria:

* Age \<12
* Pregnancy
* Active preoperative pulmonary infection
* Recent pulmonary infection (within 8 weeks)
* Active tobacco smoker
* Poorly controlled reactive airway disease (requires more than PRN albuterol)
* Non-Lung Protective Ventilation
```

## Arms

- **Vaping patients** — Includes patients that actively vape that are undergoing general anesthesia
- **Non-vaping patients** — Includes patients that do not actively vape that are undergoing general anesthesia

## Primary Outcomes

- **Perioperative pulmonary complications** _(time frame: From the initiation of general anesthesia through postoperative day seven.)_ — Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated.

## Secondary Outcomes

- **Vaping cessation timeline** _(time frame: From the initiation of general anesthesia through postoperative day seven.)_

## Locations (1)

- Naval Medical Center San Diego, San Diego, California, United States

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.naval medical center san diego|san diego|california|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT05912023.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT05912023*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*