--- title: Development of Attention and Its Relationship With Emotions in Children and Adolescents nct_id: NCT06181747 overall_status: COMPLETED phase: NA sponsor: Institute of Psychology, Chinese Academy of Sciences study_type: INTERVENTIONAL primary_condition: Attention Deficit Disorder With Hyperactivity countries: China canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06181747.md" clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06181747" ct_last_update_post_date: 2024-03-01 last_seen_at: "2026-05-12T06:43:09.685Z" source: ClinicalTrials.gov (mirrored, no enrichment) --- # Development of Attention and Its Relationship With Emotions in Children and Adolescents **Official Title:** Research on the Development of Attention and Its Relationship With Emotions in Children and Adolescents **NCT ID:** [NCT06181747](https://clinicaltrials.gov/study/NCT06181747) ## Key Facts - **Status:** COMPLETED - **Phase:** NA - **Study Type:** INTERVENTIONAL - **Target Enrollment:** 110 - **Lead Sponsor:** Institute of Psychology, Chinese Academy of Sciences - **Conditions:** Attention Deficit Disorder With Hyperactivity - **Start Date:** 2023-03-01 - **Completion Date:** 2023-05-10 - **CT.gov Last Update:** 2024-03-01 ## Brief Summary Our aim was to describe the development and usability of a mobile device-based game therapy software for ADHD. ## Detailed Description A total of 51 ADHD children and 52 healthy children were included in the study. At baseline, subjects underwent tests such as ADHD symptom-related scale assessments, computer-assisted information processing tests, and physiological-psychological tests, after which participants completed a 4-week game intervention training at home. After complete completion of the intervention, subjects repeated all tests from the baseline period and answered treatment satisfaction questions. ## Eligibility - **Minimum age:** 6 Years - **Maximum age:** 12 Years - **Sex:** ALL - **Healthy Volunteers:** Yes ``` Inclusion Criteria: * ADHD-a. Age between 6-12 years, any gender. * ADHD-b. Outpatient patients diagnosed with ADHD according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria. * ADHD-c. Patients and/or their guardians willing to participate in the study and provide informed consent. Participants aged 8 and above should also sign a child's informed consent form. * HC. The control group of healthy participants are recruited from a secondary school in Nanjing, matching the age and gender of the ADHD group. Exclusion Criteria: * a. Neurodevelopmental disorders such as cerebral palsy, epilepsy, adrenoleukodystrophy, and other similar conditions. * b. Severe mental disorders including tic disorders, autism spectrum disorders, intellectual disability, schizophrenia, bipolar disorder, depressive disorders, specific learning disorders, and other significant psychiatric conditions. * c. Individuals exhibiting ADHD-like symptoms due to hearing impairments. * d. Requirement of any central nervous system medication (including both traditional and Western medicine as well as dietary supplements) such as antipsychotics or antidepressants at any stage of the study. * e. Patients who have received systematic treatment with two different categories of ADHD medications without improvement. * f. Individuals with color blindness or any other condition that would prevent proper use of the software. * g. History of or current gaming addiction. ``` ## Arms - **ADHD group** (EXPERIMENTAL) — Participants are required to engage in game training at home for 5 days per week, with each session lasting 20-25 minutes. The game is equipped with anti-addiction measures, limiting the maximum daily game time to 30 minutes. Participants will adjust their game training based on their own abilities, and as the training progresses, the game will adaptively adjust the difficulty level and change levels accordingly. - **healthy control group** (EXPERIMENTAL) — Participants are required to engage in game training at home for 5 days per week, with each session lasting 20-25 minutes. The game is equipped with anti-addiction measures, limiting the maximum daily game time to 30 minutes. Participants will adjust their game training based on their own abilities, and as the training progresses, the game will adaptively adjust the difficulty level and change levels accordingly. ## Interventions - **a serious mobile device-based game prototype (Save the Muse Home)** (DEVICE) — The cognitive impairment corresponding to the symptoms, which we are interested in, focuses on executive inhibition, motor inhibition, sustained attention, selective attention, working memory, and planning ability. The training content will be presented in different scenarios as effective training components. The story line of the warrior breakthrough runs through the whole game, each level is adapted according to the functional damage areas of different patients, and each level involves reward and punishment mechanisms to keep the interest of the players, the difficulty gradient of each level is kept moderate, and the game includes design elements such as space, time, object attributes, actions, rules, skills, and probabilities, etc., which ultimately completes Save the Muse Home, a serious game for the treatment of ADHD. ## Primary Outcomes - **Continuous Performance Test, CPT** _(time frame: baseline and post (an average of 30days after baseline))_ — CPT software is one of the commonly used tools for examining attention and is a computer-assisted information processing test with objective results, independent of supervisors, and is the most widely used experimental paradigm in current research. The CPT paradigm adopted in this study is the presence of a white boxed area on a black background on the calculator screen, with white squares randomly appearing above or below the white boxed area, requiring the target stimulus to be a right mouse button press when the square appears below it. ## Secondary Outcomes - **Swanson Nolan, and Pelham-IV rating scales, SNAP-IV** _(time frame: baseline and post (an average of 30days after baseline))_ - **Strengths and Difficulties Questionnaire, SDQ** _(time frame: baseline and post (an average of 30days after baseline))_ - **Behavior Rating Inventory of Executive Function, BRIEF** _(time frame: baseline and post (an average of 30days after baseline))_ - **Anti-saccade task** _(time frame: baseline and post (an average of 30days after baseline))_ - **Delay-saccade task** _(time frame: baseline and post (an average of 30days after baseline))_ ## Locations (2) - Nanjing Normal University, Nanjing, Jiangsu, China - Institute of Psychology, Chinese Academy of Sciences, Beijing, China ## Recent Field Changes (last 30 days) - `results.hasResults` — added _(2026-05-12)_ - `status.overallStatus` — added _(2026-05-12)_ - `status.primaryCompletionDate` — added _(2026-05-12)_ - `status.completionDate` — added _(2026-05-12)_ - `status.lastUpdatePostDate` — added _(2026-05-12)_ - `design.phases` — added _(2026-05-12)_ - `design.enrollmentCount` — added _(2026-05-12)_ - `locations.nanjing normal university|nanjing|jiangsu|china` — added _(2026-05-12)_ - `locations.institute of psychology, chinese academy of sciences|beijing||china` — added _(2026-05-12)_ - `eligibility.criteria` — added _(2026-05-12)_ - `eligibility.minAge` — added _(2026-05-12)_ - `eligibility.maxAge` — added _(2026-05-12)_ - `eligibility.sex` — added _(2026-05-12)_ - `outcomes.primary` — added _(2026-05-12)_ - `outcomes.secondary` — added _(2026-05-12)_ - `armsInterventions.arms` — added _(2026-05-12)_ - `armsInterventions.interventions` — added _(2026-05-12)_ - `sponsor.lead` — added _(2026-05-12)_ --- *Canonical: https://parkinsonspathways.com/agent/trials/NCT06181747.md* *Source data (authoritative): https://clinicaltrials.gov/study/NCT06181747* *This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*