---
title: Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis
nct_id: NCT06298617
overall_status: COMPLETED
sponsor: Benha University
study_type: OBSERVATIONAL
primary_condition: Endometriosis
countries: Egypt
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06298617.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06298617"
ct_last_update_post_date: 2024-03-12
last_seen_at: "2026-05-12T06:02:13.497Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis

**Official Title:** Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis: A Comparative Study Versus Exploratory Laparoscopy

**NCT ID:** [NCT06298617](https://clinicaltrials.gov/study/NCT06298617)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 88
- **Lead Sponsor:** Benha University
- **Conditions:** Endometriosis
- **Start Date:** 2023-01-01
- **Completion Date:** 2023-12-25
- **CT.gov Last Update:** 2024-03-12

## Brief Summary

Endometriosis (EMs) is one of the commonest chronic inflammatory disorder affecting women and is characterized by the presence and growth of endometrial-like glandular epithelial and stromal cells outside the uterus leading to multiple clinical symptoms affecting patients quality of life and fertility with high recurrence rate . The systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) are documented as prognostic serum biomarker in many kinds of cancer and for the need and outcomes of adjuvant therapies for various cancers .

## Eligibility

- **Minimum age:** 25 Years
- **Maximum age:** 50 Years
- **Sex:** FEMALE
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Women with clinical manifestations suggestive of having EM;
* Women who was professionally diagnosed;
* Women who was diagnosed by radiologic workup;
* Women were free of exclusion criteria.

Exclusion Criteria:

* Women with EM and were maintained on treatment or underwent operative interference during the last three months;
* Patients had autoimmune diseases, maintained on immunosuppressive therapy for any indication;
* Women with cancer elsewhere in the body or receiving adjuvant therapies for cancer;
* Patients receiving therapies for viral disorders especially COVID;
* Patients refusing to undergo the exploratory laparoscopy.
```

## Arms

- **Study group**

## Interventions

- **Diagnostic laparoscopy** (PROCEDURE) — All women will undergo exploratory laparoscopy under general anesthesia
- **Full Blood Count (FBC)** (DIAGNOSTIC_TEST) — Blood samples withdrawn from patients on EDITA tubes and gone through full blood count and differential leucocytic count

## Primary Outcomes

- **Indices' ability to predict EM stage** _(time frame: 8 months)_ — Number of patients was diagnosed with EM and got staged right through a calculated indices to the patients who went for exploratory laparoscopy which improve the chances of calculated indices facing the laparoscopy.

## Locations (1)

- Benha University, Banhā, Al Qalyobia, Egypt

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.benha university|banhā|al qalyobia|egypt` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT06298617.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT06298617*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*