---
title: Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children
nct_id: NCT06472115
overall_status: RECRUITING
phase: NA
sponsor: Stanford University
study_type: INTERVENTIONAL
primary_condition: Autism Spectrum Disorder
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06472115.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06472115"
ct_last_update_post_date: 2026-02-25
last_seen_at: "2026-05-12T07:34:38.887Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

**Official Title:** A Pilot Telehealth Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

**NCT ID:** [NCT06472115](https://clinicaltrials.gov/study/NCT06472115)

## Key Facts

- **Status:** RECRUITING
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 30
- **Lead Sponsor:** Stanford University
- **Conditions:** Autism Spectrum Disorder, Autism
- **Start Date:** 2025-01-05
- **Completion Date:** 2027-10-01
- **CT.gov Last Update:** 2026-02-25

## Brief Summary

This study will examine the potential effectiveness of a virtually delivered parent-mediated intervention for insistence on sameness behaviors in autism and investigate 1) whether caregivers can learn to deliver the adapted Supportive Parenting for Anxious Childhood emotions (SPACE) intervention for IS via telehealth and 2) whether children will show greater improvement in IS behaviors.

## Eligibility

- **Minimum age:** 6 Years
- **Maximum age:** 11 Years
- **Sex:** ALL
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* 6:0 to 10:11 years at the time of consent
* diagnosed with ASD (based on history, review of available medical records including diagnostic testing completed by psychologist)
* IQ \> or = 75 (based on history, review of available medical records)
* report three or more family accommodations for insistence on sameness based on screening measures
* English-speaking parent and youth able to consistently participate in study procedures

Exclusion Criteria:

* children with significant hearing, language or motor impairment
* unstable behavioral and pharmacological treatments (e.g., anxiety medication) to treat anxiety or IS behaviors prior to two months to the start of the study and no anticipated changes in treatments during the course of the trial
* caregivers who have participated in formal SPACE training
* concurrent psychosocial treatment for anxiety or Insistence on Sameness
* children who have a history of prominent school refusal, self-harm, or suicidal ideation
```

## Arms

- **Active treatment** (EXPERIMENTAL) — Eligible participants that enroll will received 16 week parent based intervention for insistence on sameness

## Interventions

- **Supportive Parenting for Anxious Childhood Emotions (SPACE) for insistence on sameness (IS)** (BEHAVIORAL) — This study will examine the potential effectiveness of a virtually delivered parent-mediated intervention for insistence on sameness behaviors in autism. This includes a 16 week protocol where caregivers meet weekly for one hour with a study therapist.

## Primary Outcomes

- **Change from baseline in parent rated Dimensional Assessment of Restricted Behavior (DARB) Scores during treatment.** _(time frame: Screening, Baseline, Weeks 4, 8, 12, 16 and 2 month follow up)_ — DARB scores measure restricted and repetitive behaviors with higher scores indicating greater intensity.
- **Change from baseline in clinician rated clinical global impressions scale scores during treatment.** _(time frame: Weeks 8, 16 and 2 month follow up)_ — Score Range: 1 = normal, not at all ill; 7 = among the most extremely ill patients; 1 = very much informed since the initiation of treatment; 7 = very much worse since the initiation of treatment.

## Secondary Outcomes

- **Change from Baseline in Parent-Rated Anxiety as captured by the Anxiety Scale for Children with Autism Spectrum Disorder (ASC-ASD).** _(time frame: Baseline, Week 16 and 2 month Follow up)_
- **Change in Emotion Regulation Checklist scores during treatment** _(time frame: Baseline, 16 week)_
- **Change in Daily Living Skills Scale Scores during treatment** _(time frame: Baseline, 16 week, 2 month Follow up)_
- **Change in Open Source - Challenging Behavior scores during treatment** _(time frame: Baseline, 16 weeks, 2 month Follow Up)_

## Locations (1)

- Stanford University, Stanford, California, United States — _RECRUITING_

## Recent Field Changes (last 30 days)

- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.stanford university|stanford|california|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT06472115.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT06472115*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*