---
title: IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil
nct_id: NCT06480019
overall_status: RECRUITING
phase: NA
sponsor: Hospital de Clinicas de Porto Alegre
study_type: INTERVENTIONAL
primary_condition: Depression
countries: Brazil
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06480019.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06480019"
ct_last_update_post_date: 2026-04-13
last_seen_at: "2026-05-12T07:16:44.985Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil

**Official Title:** IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil: a Randomized Clinical Trial

**NCT ID:** [NCT06480019](https://clinicaltrials.gov/study/NCT06480019)

## Key Facts

- **Status:** RECRUITING
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 50
- **Lead Sponsor:** Hospital de Clinicas de Porto Alegre
- **Conditions:** Depression, Interpersonal Relations
- **Start Date:** 2024-03-01
- **Completion Date:** 2028-12-31
- **CT.gov Last Update:** 2026-04-13

## Brief Summary

Major depressive disorder is a highly prevalent, recurrent, and debilitating disease, the third cause of years of lost life in the world, and it may be the most common disease in 2030, according to the World Health Organization (WHO). Furthermore, it's also related to decreased quality of life and high mortality. Interpersonal psychotherapy (IPT) is a first-line treatment and can also be used for the prevention of depression.

This randomized controlled clinical trial is planned to have 50 participants randomized between an interventional and a control group (waiting list). Our study covers young adults (18 to 24 years old) with depression. Participants will be invited by social media to undergo treatment in an IPT group. The intervention group will be separated into groups with up to 10 participants, with a weekly meeting for eight weeks. The intervention will focus on interpersonal relationships within the model of IPT and will be held by a university student and a doctor trained in IPT.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 24 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Young adults (between 18 and 24 years old)
* Young adults who work, live or study in Porto Alegre
* PHQ ≥ 5 - without suicide ideation

Exclusion Criteria:

* Maniac or hypomanic episode
* Psychotic Syndrome
* Substance Abuse
* Suicide Risk or Ideation
```

## Arms

- **Intervention** (OTHER) — Participants that receive psychotherapy
- **Waiting list** (NO_INTERVENTION) — Participants that are waiting for intervention

## Interventions

- **Interpersonal psychotherapy** (BEHAVIORAL) — Interpersonal psychotherapy is a first-line treatment and can also be used for the prevention of depression.

## Primary Outcomes

- **Hospital Anxiety and Depression Scale (HADS)** _(time frame: Pre-treatment, Week 1 to 8)_ — The Hospital Anxiety and Depression Scale consists of 14 items, of which 7 assess anxiety and 7 assess depression. Each item is scored from 0 to 3, and each subscale has a maximum score of 21 points with higher scores indicating greater symptom severity.

## Secondary Outcomes

- **Patient Health Questionnaire-9** _(time frame: Pre-treatment, Week 1 to 8)_
- **Social support scale (MOS-SSS)** _(time frame: Pre-treatment, Week 1 to 8)_
- **Quality of Life (WHOQOL-BREF)** _(time frame: Pre-treatment, Week 1 to 8)_
- **Clinical Global Impression (CGI)** _(time frame: Pre-treatment, Week 1 to 8)_
- **Beck Depression Inventory (BDI)** _(time frame: Pre-treatment; Week 1-8)_

## Locations (1)

- Clinical Hospital for Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil — _RECRUITING_

## Recent Field Changes (last 30 days)

- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.clinical hospital for porto alegre|porto alegre|rio grande do sul|brazil` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT06480019.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT06480019*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*