---
title: In-Person Mindfulness-based Intervention for Adolescents With Autism Spectrum Disorder and Their Caregivers
nct_id: NCT06577623
overall_status: COMPLETED
phase: NA
sponsor: Southwest Autism Research & Resource Center
study_type: INTERVENTIONAL
primary_condition: Autism Spectrum Disorder
countries: United States
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06577623.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06577623"
ct_last_update_post_date: 2026-03-30
last_seen_at: "2026-05-12T06:11:57.656Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# In-Person Mindfulness-based Intervention for Adolescents With Autism Spectrum Disorder and Their Caregivers

**NCT ID:** [NCT06577623](https://clinicaltrials.gov/study/NCT06577623)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 28
- **Lead Sponsor:** Southwest Autism Research & Resource Center
- **Collaborators:** Arizona State University
- **Conditions:** Autism Spectrum Disorder, Autism
- **Start Date:** 2024-08-14
- **Completion Date:** 2026-01-30
- **CT.gov Last Update:** 2026-03-30

## Brief Summary

Adolescents with ASD often have co-occurring mental health symptoms like stress, anxiety, and depression. The investigators are conducting this research study to develop interventions for adolescents with ASD that will improve co-occurring mental health symptoms.

## Detailed Description

Adolescents with ASD and their parents will complete a 3-hour in-person screening visit to determine eligibility for the study.

Adolescents with ASD and their caregivers will participate in an 8-week mindfulness-based group intervention that meets once weekly at SARRC in Phoenix, Arizona. Each meeting will last approximately 2-hours. Teens and parents/caregivers will have separate meetings with separate group leaders but will reunite for approximately 15-minutes as a larger group to review home practice for the upcoming week. Teens and parents will each be given a free 1-year subscription to Ten Percent Happier, a commercially available mobile app focused on mindfulness meditations. Each week teens will be assigned home practice, which means we will ask participants to practice mindfulness meditation every day. The investigators will recommend specific meditations and activities to complete, but participants will have access to all mindfulness meditations on the Ten Percent Happier app.

Teens and caregivers will be asked to complete questionnaires assessing things like mood, anxiety, quality of life, mindfulness in day-to-day life, and their perception of the intervention. These questionnaires will be done immediately before the intervention, immediately after completing the intervention, and at 2-month follow-up.

## Eligibility

- **Minimum age:** 13 Years
- **Maximum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Adolescents must be ages 13 to 18 years
* Formal clinical or educational ASD diagnosis confirmed by the study team (i.e., review of the formal diagnostic or educational report)
* Must be able to attend at least 7 of the 8 in-person group meetings
* English speaking: Adolescents and their parent/caregivers must be English-speaking because the screening and behavioral measures are in English, as well as the intervention content

Exclusion Criteria:

* Non-verbal participants will be excluded to ensure test compliance and increase sample homogeneity.
* Participants with IQ scores \<70 will be excluded because the intervention was developed for individuals without intellectual disabilities.
* Participants with a physical disability or co-occurring condition that may prevent participation in the weekly group meetings (e.g., selective mutism; aggressive behavior; inability to participate in a 90-minute video conference meeting each week)
* Participants who report active suicidal ideation
```

## Arms

- **MINDful TIME group** (EXPERIMENTAL) — 8-week mindfulness-based intervention for adolescents with ASD and their caregivers. Weekly meetings will be held in-person and will last approximately 2-hours. Adolescents and their caregivers will be asked to engage in home practice outside of group meetings

## Interventions

- **MINDful TIME** (BEHAVIORAL) — Group-based psychoeducational mindfulness-based intervention.

## Primary Outcomes

- **Mean Change from Baseline in Children's Depression Inventory (CDI) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_ — Parent-report measure of adolescent depressive symptoms. Scores range from 30 to 90 with higher scores indicating higher levels of depression symptoms.
- **Mean Change from Baseline in Multidimensional Anxiety Scale for Children (MASC) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_ — Parent-report measure of adolescent anxiety symptoms. Scores range from 30 to 90 with higher scores indicating higher levels of anxiety symptoms.
- **Mean Change from Baseline in Child and Adolescent Mindfulness Measure (CAMM) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_ — Adolescent-report measure of mindfulness. Scores range from 0 to 40 with higher scores indicating higher levels of mindfulness.

## Secondary Outcomes

- **Mean Change from Baseline in Beck Youth Inventories (BYI) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_
- **Mean Change from Baseline in World Health Organization-Five Wellbeing Index (WHO-5) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_
- **Mean Change from Baseline in Adaptive Behavior Assessment System (ABAS-3) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_
- **Mean Change from Baseline in Behavior Rating Inventory of Executive Function (BRIEF) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_
- **Mean Change from Baseline in Five Facets Mindfulness Questionnaire (FFMQ) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_
- **Mean Change from Baseline in Stress Index for Parents of Adolescents (SIPA) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_
- **Mean Change from Baseline in Social Responsiveness Scale (SRS-2) Scores** _(time frame: Post-intervention (8 weeks); 2-month follow-up)_

## Locations (1)

- Southwest Autism Research and Resource Center, Phoenix, Arizona, United States

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.southwest autism research and resource center|phoenix|arizona|united states` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT06577623.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT06577623*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*