---
title: Effect of Muscle Strengthening Training with Pilates Reformer on Overweight/obese and Normal Body Weight Women (PRET)
nct_id: NCT06675162
overall_status: COMPLETED
phase: NA
sponsor: University of Thessaly
study_type: INTERVENTIONAL
primary_condition: Physiological Responses
countries: Greece
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06675162.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06675162"
ct_last_update_post_date: 2025-01-10
last_seen_at: "2026-05-12T06:14:31.885Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Effect of Muscle Strengthening Training with Pilates Reformer on Overweight/obese and Normal Body Weight Women (PRET)

**Official Title:** The Physiological Responses of Muscle Strengthening Training with Pilates Reformer in Overweight-obese Women and Women with Normal Body Weight

**NCT ID:** [NCT06675162](https://clinicaltrials.gov/study/NCT06675162)

## Key Facts

- **Status:** COMPLETED
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 20
- **Lead Sponsor:** University of Thessaly
- **Conditions:** Physiological Responses, Pilates Exercise, Overweight and Obese Women, Energy Expenditure, Strength Training
- **Start Date:** 2024-11-04
- **Completion Date:** 2025-01-07
- **CT.gov Last Update:** 2025-01-10

## Brief Summary

This study investigates the physiological responses and the metabolic burden of a Pilates Reformer strength training session in physically inactive premenopausal women with a body mass index of 18-24.9 and 25.01-39.9. The sample included 20 women divided into two groups: 10 with normal weight (NW) and 10 with overweight/obesity (OB). In a non-randomised control design, the participants will perform a 60-minute muscle-strengthening session with Pilates Reformer equipment.

## Detailed Description

Pilates Reformer (PR) is one of the most popular types of exercise worldwide and is considered a gentle and safe method for untrained and overweight people. The PR training approach has been found to contribute positively to various health conditions (vascular function, blood pressure, physical fitness, musculoskeletal problems), improving the quality of life and mental well-being of the participants. At the same time, it seems that it can have a positive effect on the lipid profile and other biochemical markers such as insulin and fasting glucose. Furthermore, muscle strengthening training with PR equipment provides better levels of mobility, increasing active range of motion, and also provides greater pelvic and trunk stability for both adult and middle-aged participants.

This study is designed to investigate the physiological and metabolic burden of a muscle-strengthening session with PR equipment in 20 pre-menopausal and physically inactive women with a body mass index (BMI) of 18-24, 99 \& 25.01-39.9, as well as to determine the contribution of energy systems (mitochondrial, glycolytic) during and after the exercise. Each training session will last approximately 60 minutes, will be led by at least one trainer, and will include a warm-up of 7-10 minutes, muscle strengthening and mobility exercises of 35 minutes, and a recovery of 5 minutes. Anthropometric indicators, dietary intake, resting heart rate, blood lactate, resting metabolic rate, muscle soreness, rate of perceived exertion, blood pressure, and performance measurements will be measured at baseline. The metabolic cost during PR training session will be estimated from heart rate, blood lactate, resting oxygen uptake, exercise oxygen uptake, and excess post-exercise oxygen consumption measurements using a portable gas analyzer. After the PR training session will be measured the rate of perceived exertion, blood pressure, blood lactate, and muscle soreness levels.

## Eligibility

- **Minimum age:** 20 Years
- **Maximum age:** 50 Years
- **Sex:** FEMALE
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Be approved for participation by an orthopedist and internist
* Have not followed any diet or nutritional supplements for weight loss in the last six months before the study
* The group with overweight/obesity will consist of women with a body mass index of 25.01 - 39.9 kg/m2
* Be physically Inactive in the last six months before the study.

Exclusion Criteria:

* Musculoskeletal injury
* Weight loss\>10% in 6 months
* \<20 years
* \>50 years
* Μenopause
* Chronic diseases
* Use of alcohol, caffeine and any type of ergogenic supplements or medication during the study
* Physically active.
```

## Arms

- **Pilates Reformer Training (OW)** (EXPERIMENTAL) — A group of women with overweight/obesity in this arm will participate in a 60-minute muscle-strengthening training session with Pilates Reformer equipment.
- **Pilates Reformer Training (NW)** (EXPERIMENTAL) — A group of women with normal weight in this arm will participate in a 60-minute muscle-strengthening training session with Pilates Reformer equipment.

## Interventions

- **Pilates Reformer Training** (OTHER) — Participants will perform a 60-minute Pilates Reformer muscle-strengthening session. The training will include a 7-10 minute warm-up, 35 minutes of muscle strengthening and mobility exercises and a 5-minute recovery. During the training, the physiological responses and the energy expenditure of the participants will be recorded.

## Primary Outcomes

- **Change in exercise-induced energy expenditure** _(time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes))_ — Exercise energy expenditure (kcal) will be measured using a portable indirect calorimetry system
- **Change in excess post-exercise oxygen consumption (EPOC)** _(time frame: At 30 minutes after the exercise session (single bout lasting 60 minutes))_ — EPOC (kcal) will be measured using a portable indirect calorimetry system
- **Change in blood lactate concentration (BLa)** _(time frame: At pre- and post-exercise session (single bout) at 4 minutes post-exercise)_ — BLa (mmol/L) concentration will be measured in a microphotometer with commercially available kits
- **Change in heart rate** _(time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes))_ — Heart rate (bpm) will be measured with a wearable heart rate monitor
- **Change in perceived exertion** _(time frame: At pre- and post-exercise session (single bout) at 4 minutes post-exercise.)_ — Rating of perceived exertion (RPE) will be measured with the Borg scale (0-10)
- **Respiratory Exchange Ratio (RER)** _(time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes))_ — Respiratory Exchange Ratio (RER) will be measured using a portable indirect calorimetry system
- **Breath Frequency (BF)** _(time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes))_ — Breath Frequency (BF) will be measured using a portable indirect calorimetry system
- **Change in oxygen consumption** _(time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes))_ — Oxygen consumption will be measured using a portable indirect calorimetry system

## Secondary Outcomes

- **Body weight** _(time frame: At baseline and at 40 minutes after the exercise session.)_
- **Body height** _(time frame: At baseline)_
- **Body mass index (BMI)** _(time frame: At baseline)_
- **Waist circumference (WC)** _(time frame: At baseline)_
- **Hip circumference (HC)** _(time frame: At baseline)_
- **Waist-to-hip ratio (WHR)** _(time frame: At baseline)_
- **Resting metabolic rate (RMR)** _(time frame: At baseline)_
- **Body fat (BF)** _(time frame: At baseline)_
- **Fat mass (FM)** _(time frame: At baseline)_
- **Fat-free mass (FFM)** _(time frame: At baseline)_
- **Bone mass density** _(time frame: At baseline)_
- **Bone mass content** _(time frame: At baseline)_
- **Peak Maximal oxygen consumption (Peak VO2)** _(time frame: At baseline)_
- **Dietary intake** _(time frame: At baseline)_
- **Systolic Blood Pressure** _(time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes))_
- **Diastolic Blood Pressure** _(time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes))_
- **Rest Heart Rate** _(time frame: At baseline)_
- **Evaluation of physical activity (PA)** _(time frame: At baseline)_

## Locations (2)

- Department of Physical Education and Sport Science, Trikala, Thessaly, Greece
- Department of Physical Education and Sports Science, University of Thessaly, Trikala, Thessaly, Greece

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.department of physical education and sport science|trikala|thessaly|greece` — added _(2026-05-12)_
- `locations.department of physical education and sports science, university of thessaly|trikala|thessaly|greece` — added _(2026-05-12)_

---

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